Meluadrine tartrate | 134865-33-1 | 134865-37-5 | β2 adrenergic receptor agonist

MedKoo Cat#: 326862 | Name: Meluadrine tartrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Meluadrine, also known as (R)-Tulobuterol; Tulobuterol-(R); HSR-81 (R); HSR-81, is an β2 adrenergic receptor agonist potentially use to prevent preterm labor.

Chemical Structure

Meluadrine tartrate

CAS#134865-37-5 (tartrate)

Theoretical Analysis

MedKoo Cat#: 326862

Name: Meluadrine tartrate

CAS#: 134865-37-5 (tartrate)

Chemical Formula: C16H24ClNO8

Exact Mass:

Molecular Weight: 393.82

Elemental Analysis: C, 48.80; H, 6.14; Cl, 9.00; N, 3.56; O, 32.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

134865-37-5 (tartrate) 134865-33-1 (free base)

Synonym

(R)-Tulobuterol; Tulobuterol-(R); HSR-81 (R); HSR-81; Meluadrine tartrate

IUPAC/Chemical Name

(R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-3-chlorophenol (2R,3R)-2,3-dihydroxysuccinate

InChi Key

VVIVBRYHTLRZGY-MBANBULQSA-N

InChi Code

InChI=1S/C12H18ClNO2.C4H6O6/c1-12(2,3)14-7-11(16)9-5-4-8(15)6-10(9)13;5-1(3(7)8)2(6)4(9)10/h4-6,11,14-16H,7H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1

SMILES Code

O[C@@H](CNC(C)(C)C)C1=CC=C(O)C=C1Cl.O=C(O)[C@H](O)[C@@H](O)C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Related CAS# CAS No. 134865-33-1(Meluadrine) CAS#134865-37-5(Meluadrine tartrate)

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 393.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Matsuda Y, Kouno S, Sakamoto H, Ikenoue T. Effects of meluadrine tartrate on maternal metabolic responses and fetal hemodynamics in pregnant goats. Jpn J Pharmacol. 2002 Oct;90(2):114-20. PubMed PMID: 12419880. 2: Matsuda Y, Kouno S, Sakamoto H, Ikenoue T. Effects of meluadrine tartrate and ritodrine hydrochloride on oxytocin-induced uterine contraction, uterine arterial blood flow and maternal cardiovascular function in pregnant goats. Jpn J Pharmacol. 2002 Oct;90(2):107-13. PubMed PMID: 12419879. 3: Matsuo K, Yamamoto Y, Kado N, Yamazaki M, Nagata O, Kato H, Tsuji A. Racemization kinetics of meluadrine tartrate in aqueous solution. Chem Pharm Bull (Tokyo). 2001 Jan;49(1):101-4. Erratum in: Chem Pharm Bull (Tokyo) 2001 Jun;49(6):794. PubMed PMID: 11201211.