MedKoo Cat#: 112171 | Name: Tetrahydroepiberberine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tetrahydroepiberberine inhibits the cytopathogenic effect of parainfluenza-3 (PI-3) virus in Vero cells and decreases the viability of HaCaT keratinocytes (IC50 = 150 µM).

Chemical Structure

Tetrahydroepiberberine
CAS#38853-67-7

Theoretical Analysis

MedKoo Cat#: 112171

Name: Tetrahydroepiberberine

CAS#: 38853-67-7

Chemical Formula: C20H21NO4

Exact Mass: 339.1471

Molecular Weight: 339.39

Elemental Analysis: C, 70.78; H, 6.24; N, 4.13; O, 18.86

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
10mg USD 750.00 2 Weeks
25mg USD 1,450.00 2 Weeks
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Related CAS #
No Data
Synonym
Tetrahydroepiberberine; Sinactine; Sinactin; (+-)-Sinactine
IUPAC/Chemical Name
8,9-dimethoxy-6,6a,11,14-tetrahydro-12H-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinoline
InChi Key
UWEHVAXMSWXKRW-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H21NO4/c1-22-18-8-13-5-6-21-10-15-12(3-4-17-20(15)25-11-24-17)7-16(21)14(13)9-19(18)23-2/h3-4,8-9,16H,5-7,10-11H2,1-2H3
SMILES Code
COC1=C(OC)C=C2C(C3N(CC4=C5OCOC5=CC=C4C3)CC2)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 339.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang Z, Li Q, Li Q, Du S, Zhou Y, Lv C, Zhao Y, Wang Y, Zhang N. Simultaneous determination of nineteen major components in Qi She Pill by ultra- high-performance liquid chromatography-tandem mass spectrometry. Acta Pharm Sin B. 2014 Oct;4(5):384-93. doi: 10.1016/j.apsb.2014.05.003. Epub 2014 Jul 15. PMID: 26579408; PMCID: PMC4629094. 2: Niu X, Li W, Xu H, Liu X, Qi L. Simultaneous quantification of 11 isoquinoline alkaloids in Corydalis impatiens (Pall.) Fisch by HPLC. J Sep Sci. 2013 Jul;36(13):2090-5. doi: 10.1002/jssc.201300036. Epub 2013 Jun 10. PMID: 23610009.