MedKoo Cat#: 556083 | Name: CIN16645 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CIN16645, also known as LP-01 lipid, is an ionizable lipid, IT is useful in lipid nanopparticle formulation for DNA and RNA vaccine delivery and Gene editing. CIN16645 was first reported in Novartis patent WO 2015095340A1. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming)..

Chemical Structure

CIN16645 HCl
CIN16645 HCl
CAS#CIN16645 HCl

Theoretical Analysis

MedKoo Cat#: 556083

Name: CIN16645 HCl

CAS#: CIN16645 HCl

Chemical Formula: C50H94ClNO9

Exact Mass: 851.6850

Molecular Weight: 888.75

Elemental Analysis: C, 67.57; H, 10.66; Cl, 3.99; N, 1.58; O, 16.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Synonym
LP-01; LP01; LP01; CIN16645; CIN-16645; CIN 16645;
IUPAC/Chemical Name
3-[4,4-Bis(octyloxy)-1-oxobutoxy]-2-[[[[3-(diethylamino)propoxy]carbonyl]oxy]methyl]propyl (9Z,12Z)-9,12-octadecadienoate hydrochloride
InChi Key
XEVNYXVZWOQZKL-ZMDOTUBMSA-N
InChi Code
InChI=1S/C50H93NO9.ClH/c1-6-11-14-17-20-21-22-23-24-25-26-27-28-29-32-36-47(52)58-43-46(45-60-50(54)57-42-35-39-51(9-4)10-5)44-59-48(53)37-38-49(55-40-33-30-18-15-12-7-2)56-41-34-31-19-16-13-8-3;/h20-21,23-24,46,49H,6-19,22,25-45H2,1-5H3;1H/b21-20-,24-23-;
SMILES Code
CCCCC/C=C\C/C=C\CCCCCCCC(OCC(COC(OCCCN(CC)CC)=O)COC(CCC(OCCCCCCCC)OCCCCCCCC)=O)=O.[H]Cl
Appearance
TBD
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Lipids and their metabolism play a crucial role in the physiology of cells, tissues, and organs. Lipids are a diverse group of hydrophobic or amphiphilic compounds that are soluble in nonpolar organic solvents and insoluble in water. There are eight major categories of lipids based on their physical properties, such as solubility and polarity: fatty acids and acyls, glycerolipids, glycerophospholipids (GPLs), sphingolipids, sterol lipids, prenol lipids, saccharolipids, and polyketides. These molecules provide structure to cellular membranes, store energy, and are vital in cell signaling and in regulating cell functions. Many inherited metabolic diseases are caused by defects in lipid metabolism. Lipid metabolism disorders often result from a harmful accumulation of unusual lipids in the blood and tissues of affected patients that can lead to damage in cells. The correct identification of these lipids is vital for proper diagnosis and treatment. Lipidomics research, a sub-discipline of metabolomics research, involves the profiling, identification and quantification of lipids within a biological source, and their interactions with other cellular components.

Preparing Stock Solutions

The following data is based on the product molecular weight 888.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL