MedKoo Cat#: 466230 | Name: VH 032 amide-PEG6-amine
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VH 032 amide-PEG6-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG6 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Chemical Structure

VH 032 amide-PEG6-amine
VH 032 amide-PEG6-amine
CAS#2763910-08-1

Theoretical Analysis

MedKoo Cat#: 466230

Name: VH 032 amide-PEG6-amine

CAS#: 2763910-08-1

Chemical Formula: C36H59Cl2N5O10S

Exact Mass: 823.3360

Molecular Weight: 824.85

Elemental Analysis: C, 52.42; H, 7.21; Cl, 8.60; N, 8.49; O, 19.40; S, 3.89

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
VH 032 amide-PEG6-amine; VH 032 amide PEG6 amine; VH 032 amide PEG6-amine; VH 032 amide-PEG6 amine;
IUPAC/Chemical Name
(2S,4R)-1-((S)-23-amino-2-(tert-butyl)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
InChi Key
BKJZEZIKOYDRIF-CTFBPPBLSA-N
InChi Code
InChI=1S/C36H57N5O10S.2ClH/c1-26-32(52-25-39-26)28-7-5-27(6-8-28)22-38-34(44)30-21-29(42)23-41(30)35(45)33(36(2,3)4)40-31(43)24-51-20-19-50-18-17-49-16-15-48-14-13-47-12-11-46-10-9-37;;/h5-8,25,29-30,33,42H,9-24,37H2,1-4H3,(H,38,44)(H,40,43);2*1H/t29-,30+,33-;;/m1../s1
SMILES Code
O=C(COCCOCCOCCOCCOCCOCCN)N[C@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)O)=O)C(C)(C)C.Cl.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 824.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL