MedKoo Cat#: 461199 | Name: Refortan

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Refortan is a hydroxyethyl starch. Used in surgery for maintaining hemostasis in patients.

Chemical Structure

Refortan
Refortan
CAS#29815-94-9

Theoretical Analysis

MedKoo Cat#: 461199

Name: Refortan

CAS#: 29815-94-9

Chemical Formula: C14H10Cl2O4

Exact Mass: 311.9956

Molecular Weight: 313.13

Elemental Analysis: C, 53.70; H, 3.22; Cl, 22.64; O, 20.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Refortan;
IUPAC/Chemical Name
2,2-bis(4-chlorophenoxy)acetic acid
InChi Key
ZKNSZZXBPSICFK-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H10Cl2O4/c15-9-1-5-11(6-2-9)19-14(13(17)18)20-12-7-3-10(16)4-8-12/h1-8,14H,(H,17,18)
SMILES Code
Clc1ccc(OC(C(O)=O)Oc2ccc(Cl)cc2)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 313.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kondrat'ev AN, Novikov VIu, Savvina IA, Driagina NV. [Using solutions of hydroxyethyl starch (6% HES 200/0.5 (refortan) and 6% HES 130/0.4 (voluven)) in neuroanesthesiology]. Anesteziol Reanimatol. 2008 Mar-Apr;(2):27-30. Russian. PubMed PMID: 18543426. 2: Kondrat'ev AN, Savvina IA, Novikov VIu, Driagina NV. [Experience with using of solutions of hydroxyethyl starch (refortan and voluven) in neuroanesthesiology]. Vestn Khir Im I I Grek. 2007;166(6):56-60. Russian. PubMed PMID: 18411744. 3: Malanov VO, Kotenko OIe, Kalaputs VI, Fomina SO. [Use of refortan in a complex therapy of intraoperative hemorrhage as a method of preservation of blood in pelvic operations in oncology patients]. Lik Sprava. 2001 Mar-Apr;(2):121-6. Ukrainian. PubMed PMID: 11519406. 4: Kryliuk VO. [Impact of infusion therapy on the indices of endogenous intoxication in severe combined trauma of the abdominal organs]. Klin Khir. 2013 Feb;(2):67-70. Ukrainian. PubMed PMID: 23705488. 5: Winterhalter M, Malinski P, Danzeisen O, Sixt S, Monaca E, Jüttner T, Peiper M, Kienbaum P, Koester A, Rahe-Meyer N. Prospective observational study for perioperative volume replacement with 6% HES 130/0,42, 4% gelatin and 6% HES 200/0,5 in cardiac surgery. Eur J Med Res. 2010 Sep 24;15(9):383-9. PubMed PMID: 20952347; PubMed Central PMCID: PMC3351905. 6: Moskalev VV, Dolgikh VT, Strakh AP, Lukach VN. [Comparative evaluation of different infusion medias used in therapy for neonatal hypovolemia]. Anesteziol Reanimatol. 2005 Jan-Feb;(1):32-5. Russian. PubMed PMID: 15839221.