MedKoo Cat#: 465795 | Name: Histidyltyrosine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Histidyltyrosine is a novel enhancer of catalytic efficiency of neurolysin.

Chemical Structure

Histidyltyrosine
Histidyltyrosine
CAS#35979-00-1

Theoretical Analysis

MedKoo Cat#: 465795

Name: Histidyltyrosine

CAS#: 35979-00-1

Chemical Formula: C15H18N4O4

Exact Mass: 318.1328

Molecular Weight: 318.33

Elemental Analysis: C, 56.60; H, 5.70; N, 17.60; O, 20.10

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Histidyltyrosine; His-Tyr; HisTyr; His Tyr;
IUPAC/Chemical Name
L-histidyl-L-tyrosine
InChi Key
HTOOKGDPMXSJSY-STQMWFEESA-N
InChi Code
InChI=1S/C15H18N4O4/c16-12(6-10-7-17-8-18-10)14(21)19-13(15(22)23)5-9-1-3-11(20)4-2-9/h1-4,7-8,12-13,20H,5-6,16H2,(H,17,18)(H,19,21)(H,22,23)/t12-,13-/m0/s1
SMILES Code
O=C(O)[C@@H](NC([C@@H](N)CC1=CNC=N1)=O)CC2=CC=C(O)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 318.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Weryński A, Waniewski J, Wang T, Anderstam B, Lindholm B, Bergström J. Comparison of kinetic characteristics of amino acid-based and dipeptide-based peritoneal dialysis solutions. Int J Artif Organs. 2006 Jul;29(7):681-90. doi: 10.1177/039139880602900706. PMID: 16874673. 2: Tanner C, Navaratnam S, Parsons BJ. Intramolecular electron transfer in the dipeptide, histidyltyrosine: a pulse radiolysis study. Free Radic Biol Med. 1998 Mar 1;24(4):671-8. doi: 10.1016/s0891-5849(97)00340-7. PMID: 9559880. 3: Jean PA, Reed DJ. In vitro dipeptide, nucleoside, and glutathione alkylation by S-(2-chloroethyl)glutathione and S-(2-chloroethyl)-L-cysteine. Chem Res Toxicol. 1989 Nov-Dec;2(6):455-60. doi: 10.1021/tx00012a016. PMID: 2519737.