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MedKoo Cat#: 462758 | Name: Historphin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Historphin is an opioid peptide from histone H4.

Chemical Structure

Historphin
Historphin
CAS#105250-85-9

Theoretical Analysis

MedKoo Cat#: 462758

Name: Historphin

CAS#: 105250-85-9

Chemical Formula: C24H29N5O7

Exact Mass: 499.2067

Molecular Weight: 499.52

Elemental Analysis: C, 57.71; H, 5.85; N, 14.02; O, 22.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Tyr-gly-phe-gly-gly;
IUPAC/Chemical Name
L-tyrosylglycyl-L-phenylalanylglycylglycine
InChi Key
BGFPKYKDLYYTJH-OALUTQOASA-N
InChi Code
InChI=1S/C24H29N5O7/c25-18(10-16-6-8-17(30)9-7-16)23(35)27-13-21(32)29-19(11-15-4-2-1-3-5-15)24(36)28-12-20(31)26-14-22(33)34/h1-9,18-19,30H,10-14,25H2,(H,26,31)(H,27,35)(H,28,36)(H,29,32)(H,33,34)/t18-,19-/m0/s1
SMILES Code
N[C@H](C(NCC(N[C@H](C(NCC(NCC(O)=O)=O)=O)Cc1ccccc1)=O)=O)Cc2ccc(O)cc2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 499.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kharchenko EP, Kalikhevich VN, Sokolova TV, Shestak KI, Ardemasova ZA. Vysokoaktivnye analogi opiatopodobnykh peptidov gistorfina i kapporfina [Highly active analogs of opiate-like peptides historphin and kapporphin]. Vopr Med Khim. 1989 Mar-Apr;35(2):106-9. Russian. PMID: 2500779.

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