Synonym
Benzenepentanol, Oxyphyllacinol
IUPAC/Chemical Name
1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol
InChi Key
DHUCMVAZNHOIPY-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H26O3/c1-23-20-15-17(12-14-19(20)22)11-13-18(21)10-6-5-9-16-7-3-2-4-8-16/h2-4,7-8,12,14-15,18,21-22H,5-6,9-11,13H2,1H3
SMILES Code
OC(CCCCC1=CC=CC=C1)CCC2=CC=C(O)C(OC)=C2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Biological target:
Oxyphyllacinol is an antioxidant.
In vitro activity:
Results from LC-MS/MS analysis showed that the water and chloroform fractions of S. nodiflora have more than 20 compounds. The dominant compounds on water fractions, primarily oxyphyllacinol, valine, and sugiol, were reported as having strong antioxidant activity in vitro and in the cell line model.
Reference: Adv Pharmacol Pharm Sci. 2021 Sep 18;2021:2119634. https://pubmed.ncbi.nlm.nih.gov/34589709/
|
Solvent |
mg/mL |
mM |
| Solubility |
| TBD |
0.0 |
0.00 |
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
314.43
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
Formulation protocol:
1. Astuti RI, Prastya ME, Batubara I, Budiarti E, Ilmiyawati A. Antiaging and Antioxidant Bioactivities of Asteraceae Plant Fractions on the Cellular Functions of the Yeast Schizosaccharomyces pombe. Adv Pharmacol Pharm Sci. 2021 Sep 18;2021:2119634. doi: 10.1155/2021/2119634. PMID: 34589709; PMCID: PMC8476265.
In vitro protocol:
1. Astuti RI, Prastya ME, Batubara I, Budiarti E, Ilmiyawati A. Antiaging and Antioxidant Bioactivities of Asteraceae Plant Fractions on the Cellular Functions of the Yeast Schizosaccharomyces pombe. Adv Pharmacol Pharm Sci. 2021 Sep 18;2021:2119634. doi: 10.1155/2021/2119634. PMID: 34589709; PMCID: PMC8476265.
1: Astuti RI, Prastya ME, Batubara I, Budiarti E, Ilmiyawati A. Antiaging and Antioxidant Bioactivities of Asteraceae Plant Fractions on the Cellular Functions of the Yeast Schizosaccharomyces pombe. Adv Pharmacol Pharm Sci. 2021 Sep 18;2021:2119634. doi: 10.1155/2021/2119634. PMID: 34589709; PMCID: PMC8476265.
2: Chen F, Li HL, Tan YF, Li YH, Lai WY, Guan WW, Zhang JQ, Zhao YS, Qin ZM. Identification of known chemicals and their metabolites from Alpinia oxyphylla fruit extract in rat plasma using liquid chromatography/tandem mass spectrometry (LC-MS/MS) with selected reaction monitoring. J Pharm Biomed Anal. 2014 Aug;97:166-77. doi: 10.1016/j.jpba.2014.04.037. Epub 2014 May 10. PMID: 24879483.
3: Chen F, Li HL, Tan YF, Guan WW, Zhang JQ, Li YH, Zhao YS, Qin ZM. Different accumulation profiles of multiple components between pericarp and seed of Alpinia oxyphylla capsular fruit as determined by UFLC-MS/MS. Molecules. 2014 Apr 10;19(4):4510-23. doi: 10.3390/molecules19044510. PMID: 24727421; PMCID: PMC6271690.
4: Zeng P, Liu YC, Wang XM, Ye CY, Sun YW, Su HF, Qiu SW, Li YN, Wang Y, Wang YC, Ma J, Li M, Tian Q. Targets and mechanisms of Alpinia oxyphylla Miquel fruits in treating neurodegenerative dementia. Front Aging Neurosci. 2022 Nov 30;14:1013891. doi: 10.3389/fnagi.2022.1013891. PMID: 36533181; PMCID: PMC9749063.
5: Huo C, Han F, Xiao Y, Kim HJ, Lee IS. Microbial Transformation of Yakuchinone A and Cytotoxicity Evaluation of Its Metabolites. Int J Mol Sci. 2022 Apr 3;23(7):3992. doi: 10.3390/ijms23073992. PMID: 35409351; PMCID: PMC9000044.
