Furomine | CAS#142996-66-5 | Ligand

MedKoo Cat#: 534662 | Name: Furomine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Furomine is a ligand.

Chemical Structure

Furomine

CAS#142996-66-5

Theoretical Analysis

MedKoo Cat#: 534662

Name: Furomine

CAS#: 142996-66-5

Chemical Formula: C20H32N2O4

Exact Mass: 364.2362

Molecular Weight: 364.49

Elemental Analysis: C, 65.91; H, 8.85; N, 7.69; O, 17.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Furomine

IUPAC/Chemical Name

4,4'-(Ethylenebis(iminomethylidyne))bis(dihydro-2,2,5,5-tetramethyl-3(2H)-furanone)

InChi Key

WTJNRTWSVRJUNX-XSYHWHKQSA-N

InChi Code

InChI=1S/C20H32N2O4/c1-17(2)13(15(23)19(5,6)25-17)11-21-9-10-22-12-14-16(24)20(7,8)26-18(14,3)4/h11-12,21-22H,9-10H2,1-8H3/b13-11-,14-12-

SMILES Code

O=C1C(C)(C)OC(C)(C)/C1=C\NCCN/C=C2C(C(C)(C)OC/2(C)C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 364.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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Quantification of Furosine (Nε-(2-Furoylmethyl)-l-lysine) in Different Parts of Velvet Antler with Various Processing Methods and Factors Affecting Its Formation. Molecules. 2019 Mar 31;24(7):1255. doi: 10.3390/molecules24071255. PMID: 30935092; PMCID: PMC6479359. 5: Li H, Xing L, Zhao N, Wang J, Zheng N. Furosine Induced Apoptosis by the Regulation of STAT1/STAT2 and UBA7/UBE2L6 Genes in HepG2 Cells. Int J Mol Sci. 2018 May 31;19(6):1629. doi: 10.3390/ijms19061629. PMID: 29857509; PMCID: PMC6032202. 6: Erbersdobler HF, Somoza V. Forty years of furosine - forty years of using Maillard reaction products as indicators of the nutritional quality of foods. Mol Nutr Food Res. 2007 Apr;51(4):423-30. doi: 10.1002/mnfr.200600154. PMID: 17390403. 7: Saeed Y, Wang JQ, Zheng N. Furosine induces DNA damage and cell death in selected human cell lines: a strong toxicant to kidney Hek-293 cells. Food Sci Biotechnol. 2017 Aug 30;26(4):1093-1101. doi: 10.1007/s10068-017-0131-1. PMID: 30263641; PMCID: PMC6049533. 8: Mesías M, Sáez-Escudero L, Morales FJ, Delgado-Andrade C. Occurrence of Furosine and Hydroxymethylfurfural in Breakfast Cereals. Evolution of the Spanish Market from 2006 to 2018. Foods. 2019 May 10;8(5):158. doi: 10.3390/foods8050158. PMID: 31083379; PMCID: PMC6560387. 9: Li Y, Liu X, Meng L, Wang Y. Qualitative and quantitative analysis of furosine in fresh and processed ginsengs. J Ginseng Res. 2018 Jan;42(1):21-26. doi: 10.1016/j.jgr.2016.12.004. Epub 2017 Jan 10. PMID: 29348718; PMCID: PMC5766691. 10: Giannetti V, Mariani MB, Mannino P. Furosine as a pasta quality marker: evaluation by an innovative and fast chromatographic approach. J Food Sci. 2013 Jul;78(7):C994-9. doi: 10.1111/1750-3841.12163. Epub 2013 Jun 14. PMID: 23772758. 11: Marconi E, Caboni MF, Messia MC, Panfili G. Furosine: a suitable marker for assessing the freshness of royal jelly. J Agric Food Chem. 2002 May 8;50(10):2825-9. doi: 10.1021/jf0114987. PMID: 11982406. 12: Artavia G, Rojas-Bogantes L, Granados-Chinchilla F. Two alternative chromatography methods assisted by the sulfonic acid moeity for the determination of furosine in milk. MethodsX. 2018 Jun 15;5:639-647. doi: 10.1016/j.mex.2018.06.007. PMID: 30013947; PMCID: PMC6019685. 13: Boucher SE, Pedersen C, Stein HH, Schwab CG. Evaluation of the furosine and homoarginine methods for determining reactive lysine in rumen-undegraded protein. J Dairy Sci. 2009 Aug;92(8):3951-8. doi: 10.3168/jds.2008-1993. PMID: 19620678. 14: Montilla A, Megías-Pérez R, Olano A, Villamiel M. Presence of galactooligosaccharides and furosine in special dairy products designed for elderly people. Food Chem. 2015 Apr 1;172:481-5. doi: 10.1016/j.foodchem.2014.09.079. Epub 2014 Sep 20. PMID: 25442582. 15: Fratianni A, Niro S, Messia MC, Cinquanta L, Panfili G, Albanese D, Di Matteo M. Kinetics of carotenoids degradation and furosine formation in dried apricots (Prunus armeniaca L.). 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