Wy 25093 | CAS#72807-01-3 | inhibitor

MedKoo Cat#: 585427 | Name: Wy 25093

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Wy 25093 is an inhibitor of the neuronal 5-hydroxytryptamine (5-HT) uptake process in vitro and in vivo, and may possess potential antidepressant activity.

Chemical Structure

Wy 25093

CAS#72807-01-3

Theoretical Analysis

MedKoo Cat#: 585427

Name: Wy 25093

CAS#: 72807-01-3

Chemical Formula: C22H24N4O2

Exact Mass: 376.1899

Molecular Weight: 376.46

Elemental Analysis: C, 70.19; H, 6.43; N, 14.88; O, 8.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Wy 25093; Wy25093; Wy-25093

IUPAC/Chemical Name

N-[[1-(1H-indol-3-ylmethyl)piperidin-4-yl]carbamoyl]benzamide

InChi Key

LBRHJTCPPZIPJU-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H24N4O2/c27-21(16-6-2-1-3-7-16)25-22(28)24-18-10-12-26(13-11-18)15-17-14-23-20-9-5-4-8-19(17)20/h1-9,14,18,23H,10-13,15H2,(H2,24,25,27,28)

SMILES Code

O=C(NC(NC1CCN(CC2=CNC3=C2C=CC=C3)CC1)=O)C4=CC=CC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 376.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Diggory GL, Stephens RJ, Dickison SE, Moser P, Wood MD. Behavioural and neurochemical proteins of 1-[1-([indol-3-yl] methyl) piperid-4-yl]-3-benzoylurea (Wy 25093) in rodents. Arch Int Pharmacodyn Ther. 1980 Nov;248(1):86-104. PubMed PMID: 6971080. 2: James TA, Starr MS. Rotational behaviour elicited by 5-HT in the rat: evidence for an inhibitory role of 5-HT in the substantia nigra and corpus striatum. J Pharm Pharmacol. 1980 Mar;32(3):196-200. PubMed PMID: 6103936. 3: Hodges HM, Green S. Evidence for the involvement of brain GABA and serotonin systems in the anticonflict effects of chlordiazepoxide in rats. Behav Neural Biol. 1984 Mar;40(2):127-54. PubMed PMID: 6329160.