MedKoo Cat#: 415016 | Name: Pirtenidine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pirtenidine is effective for the control of plaque & gingivitis.

Chemical Structure

Pirtenidine
Pirtenidine
CAS#103923-27-9 (free base)

Theoretical Analysis

MedKoo Cat#: 415016

Name: Pirtenidine

CAS#: 103923-27-9 (free base)

Chemical Formula: C21H38N2

Exact Mass: 318.3035

Molecular Weight: 318.55

Elemental Analysis: C, 79.18; H, 12.02; N, 8.79

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
100mg USD 925.00 2 Weeks
250mg USD 1,650.00 2 Weeks
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Synonym
Pirtenidine; Pirtenidina; Pirtenidinum
IUPAC/Chemical Name
1,4-Dihydro-1-octyl-4-(octylimino)pyridine
InChi Key
RGTPDNXJDCPXAB-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H38N2/c1-3-5-7-9-11-13-17-22-21-15-19-23(20-16-21)18-14-12-10-8-6-4-2/h15-16,19-20H,3-14,17-18H2,1-2H3
SMILES Code
CCCCCCCC/N=C1C=CN(CCCCCCCC)C=C/1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 318.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ghannoum MA, Elteen KA, Ellabib M, Whittaker PA. Antimycotic effects of octenidine and pirtenidine. J Antimicrob Chemother. 1990 Feb;25(2):237-45. doi: 10.1093/jac/25.2.237. PMID: 2184158. 2: Ellabib M, Ghannoum MA, Whittaker PA. Effects of the pyridinamines octenidine and pirtenidine on yeast mitochondrial function. Biochem Soc Trans. 1990 Apr;18(2):342-3. doi: 10.1042/bst0180342. PMID: 2199275. 3: Ghannoum MA, Moussa NM, Whittaker P, Swairjo I, Abu-Elteen KH. Subinhibitory concentration of octenidine and pirtenidine: influence on the lipid and sterol contents of Candida albicans. Chemotherapy. 1992;38(1):46-56. doi: 10.1159/000238941. PMID: 1618003. 4: Ghannoum MA, Abu Elteen K, Stretton RJ, Whittaker PA. Effects of octenidine and pirtenidine on adhesion of Candida species to human buccal epithelial cells in vitro. Arch Oral Biol. 1990;35(4):249-53. doi: 10.1016/0003-9969(90)90039-d. PMID: 2378578. 5: Powles P, Usansky JI, Franklin RA. The pharmacokinetics of pirtenidine in the rat and dog. Xenobiotica. 1989 Dec;19(12):1349-54. doi: 10.3109/00498258909043186. PMID: 2618086. 6: Wentland MP, Bailey DM, Powles RG, Slee AM, Sedlock DM. The in vitro dental plaque inhibitory properties of a series of N-[1-alkyl-4(1H)-pyridinylidene]alkylamines. J Med Chem. 1988 Oct;31(10):2024-7. doi: 10.1021/jm00118a030. PMID: 3172139.