MedKoo Cat#: 577061 | Name: Meclofenamate sodium
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Meclofenamate sodium is a potent nonsteroidal antiinflammatory agent, specifically inhibits chemotactic factor-induced human polymorphonuclear leukocyte functions: chemotaxis, degranulation, and generation of superoxide anion radicals.

Chemical Structure

Meclofenamate sodium
Meclofenamate sodium
CAS#6385-02-0 (sodium)

Theoretical Analysis

MedKoo Cat#: 577061

Name: Meclofenamate sodium

CAS#: 6385-02-0 (sodium)

Chemical Formula: C14H10Cl2NNaO2

Exact Mass: 316.9986

Molecular Weight: 318.13

Elemental Analysis: C, 52.86; H, 3.17; Cl, 22.29; N, 4.40; Na, 7.23; O, 10.06

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
5g USD 450.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Synonym
CI 583; CI583; CI-583; INF 4668; INF4668; INF-4668; Meclofenamate sodium; Sodium meclofenamate
IUPAC/Chemical Name
Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, monosodium salt
InChi Key
OGPIIGMUPMPMNT-UHFFFAOYSA-M
InChi Code
InChI=1S/C14H11Cl2NO2.Na/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19;/h2-7,17H,1H3,(H,18,19);/q;+1/p-1
SMILES Code
[Na+].Cc1ccc(Cl)c(Nc2ccccc2C(=O)[O-])c1Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 318.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ghosh R, Hwang SM, Cui Z, Gilda JE, Gomes AV. Different effects of the nonsteroidal anti-inflammatory drugs meclofenamate sodium and naproxen sodium on proteasome activity in cardiac cells. J Mol Cell Cardiol. 2016 May;94:131-44. doi: 10.1016/j.yjmcc.2016.03.016. Epub 2016 Apr 3. PubMed PMID: 27049794. 2: Mongini F, Bona G, Garnero M, Gioria A. Efficacy of meclofenamate sodium versus placebo in headache and craniofacial pain. Headache. 1993 Jan;33(1):22-8. PubMed PMID: 8436494. 3: Benassi L, Bertani D, Avanzini A. An attempt at real prophylaxis of primary dysmenorrhea: comparison between meclofenamate sodium and naproxen sodium. Clin Exp Obstet Gynecol. 1993;20(2):102-7. PubMed PMID: 8330429. 4: Conroy MC, Randinitis EJ, Turner JL. Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium. Clin J Pain. 1991;7 Suppl 1:S44-8. Review. PubMed PMID: 1810520.