Meclofenamate sodium is a potent nonsteroidal anti-inflammatory agent, specifically inhibits chemotactic factor-induced human polymorphonuclear leukocyte functions: chemotaxis, degranulation, and generation of superoxide anion radicals. These effects of MSM were found to be dependent upon the concentrations of drug not bound to albumin (free drug), and were caused by its ability to interfere at both a receptor and post-receptor (i.e., a step distal to mobilization of polymorphonuclear leukocyte intracellular Ca2+) level.
MedKoo Cat#: 525606
Name: Meclofenamate sodium hydrate
CAS#: 67254-91-5 (sodium hydrate)
Chemical Formula: C14H12Cl2NNaO3
Exact Mass: 0.0000
Molecular Weight: 336.14
Elemental Analysis: C, 50.02; H, 3.60; Cl, 21.09; N, 4.17; Na, 6.84; O, 14.28
The following data is based on the product molecular weight 336.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
