Nnc 09-0026 | CAS# 141360-03-4 | neuronal calcium channel blocker

MedKoo Cat#: 414440 | Name: Nnc 09-0026

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nnc 09-0026 is a neuronal calcium channel blocker

Chemical Structure

Nnc 09-0026

CAS#141360-03-4

Theoretical Analysis

MedKoo Cat#: 414440

Name: Nnc 09-0026

CAS#: 141360-03-4

Chemical Formula: C25H35Cl2F3N2O

Exact Mass: 506.2079

Molecular Weight: 507.46

Elemental Analysis: C, 59.17; H, 6.95; Cl, 13.97; F, 11.23; N, 5.52; O, 3.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Nnc09-0026; Nnc-09-0026; Nnc 09-0026

IUPAC/Chemical Name

Benzenamine, 4-(1-butyl-3-((4-(trifluoromethyl)phenoxy)methyl)-4-piperidinyl)-N,N-dimethyl-, dihydrochloride, trans-(-)-

InChi Key

VAJHWBBBDAHYRE-OYNPXDHBSA-N

InChi Code

InChI=1S/C25H33F3N2O.2ClH/c1-4-5-15-30-16-14-24(19-6-10-22(11-7-19)29(2)3)20(17-30)18-31-23-12-8-21(9-13-23)25(26,27)28;;/h6-13,20,24H,4-5,14-18H2,1-3H3;2*1H/t20-,24-;;/m1../s1

SMILES Code

CN(C)C1=CC=C([C@@H]2[C@@H](COC3=CC=C(C(F)(F)F)C=C3)CN(CCCC)CC2)C=C1.[H]Cl.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 507.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: O'Neill MJ, Bath CP, Dell CP, Hicks CA, Gilmore J, Ambler SJ, Ward MA, Bleakman D. Effects of Ca2+ and Na+ channel inhibitors in vitro and in global cerebral ischaemia in vivo. Eur J Pharmacol. 1997 Aug 6;332(2):121-31. doi: 10.1016/s0014-2999(97)01074-1. PMID: 9286613. 2: Barone FC, Price WJ, Jakobsen P, Sheardown MJ, Feuerstein G. Pharmacological profile of a novel neuronal calcium channel blocker includes reduced cerebral damage and neurological deficits in rat focal ischemia. Pharmacol Biochem Behav. 1994 May;48(1):77-85. doi: 10.1016/0091-3057(94)90501-0. PMID: 8029306. 3: Hicks CA, Ward MA, O'Neill MJ. Neuroprotective effects of the neuronal Ca(2+) channel blockers, LY042826 and LY393615 in vivo. Eur J Pharmacol. 2000 Nov 24;408(3):241-8. doi: 10.1016/s0014-2999(00)00784-6. PMID: 11090640.