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MedKoo Cat#: 565445 | Name: SSYA10-001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SSYA10-001, also known as DSHS 00884 and CCG-45281, a non-toxic human papillomavirus E6 inhibitor and is a replication inhibitor of severe acute respiratory syndrome (SARS), mouse hepatitis, and Middle East respiratory syndrome coronaviruses.

Chemical Structure

SSYA10-001
CAS#675104-49-1 (free base)

Theoretical Analysis

MedKoo Cat#: 565445

Name: SSYA10-001

CAS#: 675104-49-1 (free base)

Chemical Formula: C12H12N4O2S2

Exact Mass: 308.0402

Molecular Weight: 308.37

Elemental Analysis: C, 46.74; H, 3.92; N, 18.17; O, 10.38; S, 20.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
675104-49-1 (free base) SSYA10-001 HCl
Synonym
SSYA10001; SSYA10 001; SSYA10-001; DSHS00884; DSHS-00884; DSHS 00884; CCG-45281; CCG 45281; CCG45281;
IUPAC/Chemical Name
3-[(2-Nitrophenyl)sulfanylmethyl]-4-prop-2-enyl-1H-1,2,4-triazole-5-thione
InChi Key
VWFIHGWHMXSTAO-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H12N4O2S2/c1-2-7-15-11(13-14-12(15)19)8-20-10-6-4-3-5-9(10)16(17)18/h2-6H,1,7-8H2,(H,14,19)
SMILES Code
S=C1N(CC=C)C(CSC2=CC=CC=C2[N+]([O-])=O)=NN1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 308.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Adedeji AO, Singh K, Kassim A, Coleman CM, Elliott R, Weiss SR, Frieman MB, Sarafianos SG. Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. Antimicrob Agents Chemother. 2014 Aug;58(8):4894-8. doi: 10.1128/AAC.02994-14. Epub 2014 May 19. PubMed PMID: 24841268; PubMed Central PMCID: PMC4136041. 2: Adedeji AO, Singh K, Calcaterra NE, DeDiego ML, Enjuanes L, Weiss S, Sarafianos SG. Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase. Antimicrob Agents Chemother. 2012 Sep;56(9):4718-28. doi: 10.1128/AAC.00957-12. Epub 2012 Jun 25. PubMed PMID: 22733076; PubMed Central PMCID: PMC3421890.