IUPAC/Chemical Name
2-(2-(4-Benzhydrylpiperazin-1-yl)ethoxy)ethanol
InChi Key
OXBBIHZWNDPBMQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H28N2O2/c24-16-18-25-17-15-22-11-13-23(14-12-22)21(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-10,21,24H,11-18H2
SMILES Code
OCCOCCN1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
340.47
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Li QY, Zhuo ZL, Chen YW. [Simultaneous determination of three components in compound clorprenaline tablet by using the derivative-complementary tristimulus method]. Yao Xue Xue Bao. 1990;25(5):357-61. Chinese. PubMed PMID: 2284956.
2: Kiehelä J, Keskinen H, Hohenthal TT. Clinical investigation of a new broncholyticum--decloxizine--as compared with franol and placebo treatment. Respiration. 1970;27(6):582-90. PubMed PMID: 4395228.
3: Daly MJ, Lightowler JE. Effect of decloxizine on histamine aerosol induced bronchoconstriction in the conscious guinea-pig. Arch Int Pharmacodyn Ther. 1969 Nov;182(1):215-8. PubMed PMID: 4391496.
4: Muittari A, Mattila MJ, Patiala J. Bronchodilator action of drug combinations in asthmatic patients: decloxizine, orciprenaline, and ephedrine. Ann Allergy. 1969 Jun;27(6):274-9. PubMed PMID: 4891707.
5: Installe E, Himmer P. [Preliminary study of effects of decloxizine on air passage resistance in chronic bronchitis patients]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):756-64. French. PubMed PMID: 5739763.
6: Herberg D. [Study of the effect of decloxizine on respiratory resistance of patients with obstructive bronchopulmonary disease]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):752-5. German. PubMed PMID: 5739762.
7: Mottard L, Petit JM. [Protective effect of decloxizine in relation to bronchospasm due to histamine]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):749-51. French. PubMed PMID: 5739761.
8: Hrouda J, Bogaard JM. [Results from comparative study of the bronchodilator effect of decloxizine in patients with reversible bronchospasm]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):742-8. Dutch. PubMed PMID: 5739760.
9: Geubelle F, Senterre J. [Clinical experimentation with a new synthetic bronchodilator: decloxizine]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):724-41. French. PubMed PMID: 5739759.
10: Streumer J, Jolie R, de Groef L. [Vitalograph results with decloxizine for asthmatic children]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):685-94. Dutch. PubMed PMID: 5739756.
11: van Mechelen J. [Effect of decloxizine on asthmatic children]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):667-74. Dutch. PubMed PMID: 5739755.
12: Detry JM. [Study of decloxizine activity by measurement of peak expiratory flow]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):653-60. French. PubMed PMID: 5739754.
13: Herberg D. [Study of the effect of decloxizine on central CO2 sensitive respiratory regulation of lung disease patients and arterial CO2 pressure in patients with bronchial obstruction and alveolar hypoventilation]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):643-6. German. PubMed PMID: 5739753.
14: Linehan WD. Influence of decloxizine upon the arterial oxygen saturation. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):637-42. PubMed PMID: 5739752.
15: Vaerenberg C. [Study of the possible effect of decloxizine on blood gas levels]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):633-6. Dutch. PubMed PMID: 5739751.
16: de Coster A. [Evaluation of effects of decloxizine on blood gas and pulmonary hemodynamics]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):625-32. French. PubMed PMID: 5739750.
17: Blasi A, Di Perna A. [Influence of decloxizine on various spirometric indices]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):591-600. French. PubMed PMID: 5739748.
18: Scarpa GL. [Effects of decloxizine on clinical symptomatology, respiratory function and cutaneous reaction to serotonin in asthmatic patients]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):583-90. French. PubMed PMID: 5739747.
19: Verhaegen H, de Beukelaar A. [Comparative clinical study of decloxizine by spirographic function tests]. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):554-61. Dutch. PubMed PMID: 5739746.
20: Linehan WD. Clinical results obtained with decloxizine by spirographic methods. Acta Tuberc Pneumol Belg. 1968 Jul-Oct;59(4):549-53. PubMed PMID: 5739745.