MDL-28753 | CAS# 129509-46-2 | Biochemical

MedKoo Cat#: 577010 | Name: MDL-28753

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDL-28753 is an antagonist of leukotriene D4 and antagonist of leukotrine C4.

Chemical Structure

MDL-28753

CAS#129509-46-2

Theoretical Analysis

MedKoo Cat#: 577010

Name: MDL-28753

CAS#: 129509-46-2

Chemical Formula: C27H40O5S

Exact Mass: 476.2596

Molecular Weight: 476.67

Elemental Analysis: C, 68.03; H, 8.46; O, 16.78; S, 6.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MDL28753; MDL 28753; MDL-28753

IUPAC/Chemical Name

Cyclohexanecarboxylic acid, 4-(1-((2-carboxyethyl)thio)-11-phenyl-2-undecenyl)-4-hydroxy-, (4(S)-(1alpha,4beta,4(Z)))-

InChi Key

NHVMAVIXHNUKST-DSHVXGAESA-N

InChi Code

InChI=1S/C27H40O5S/c28-25(29)18-21-33-24(27(32)19-16-23(17-20-27)26(30)31)15-11-6-4-2-1-3-5-8-12-22-13-9-7-10-14-22/h7,9-11,13-15,23-24,32H,1-6,8,12,16-21H2,(H,28,29)(H,30,31)/b15-11-/t23-,24-,27-/m0/s1

SMILES Code

OC(=O)CCS[C@@H](\C=C/CCCCCCCCc1ccccc1)[C@@]2(O)CC[C@H](CC2)C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 476.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Gieske TH, Sabol JS, Raddatz R. MDL 28,753, an agonist of LTD4 but an antagonist of LTC4 in longitudinal muscle of guinea pig ileum. J Pharmacol Exp Ther. 1990 Jul;254(1):192-7. PMID: 2164091.