SBP-0636457 is a Smac mimetic. It demonstrates potent cell-killing effects in several subtypes of breast, ovarian, and prostate cancer cell lines, but only when the DR ligand TRAIL or another such apoptosis inducer is co-administered.
MedKoo Cat#: 563815
Name: SBP-0636457
CAS#: 1422180-49-1 (free base)
Chemical Formula: C25H36N4O4
Exact Mass: 456.2737
Molecular Weight: 456.59
Elemental Analysis: C, 65.77; H, 7.95; N, 12.27; O, 14.02
The following data is based on the product molecular weight 456.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
