MedKoo Cat#: 126528 | Name: GLUT inhibitor-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively.

Chemical Structure

GLUT inhibitor-1
GLUT inhibitor-1
CAS#2421141-40-2

Theoretical Analysis

MedKoo Cat#: 126528

Name: GLUT inhibitor-1

CAS#: 2421141-40-2

Chemical Formula: C32H35N7O2

Exact Mass: 549.2852

Molecular Weight: 549.68

Elemental Analysis: C, 69.92; H, 6.42; N, 17.84; O, 5.82

Price and Availability

Size Price Availability Quantity
50mg USD 2,650.00 2 Weeks
100mg USD 3,650.00 2 Weeks
1g USD 6,950.00 2 Weeks
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Related CAS #
No Data
Synonym
GLUT inhibitor 1; GLUT inhibitor-1; GLUT inhibitor1
IUPAC/Chemical Name
2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-cyclobutyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenoxy)-N-(1-methylcyclopropyl)acetamide
InChi Key
IXZVJTRRPOHKJF-UHFFFAOYSA-N
InChi Code
InChI=1S/C32H35N7O2/c1-32(13-14-32)38-29(40)20-41-26-7-2-4-22(16-26)30-36-28-12-15-39(25-5-3-6-25)19-27(28)31(37-30)35-24-10-8-21(9-11-24)23-17-33-34-18-23/h2,4,7-11,16-18,25H,3,5-6,12-15,19-20H2,1H3,(H,33,34)(H,38,40)(H,35,36,37)
SMILES Code
O=C(COC1=CC=CC(C2=NC(CCN(C3CCC3)C4)=C4C(NC5=CC=C(C6=CNN=C6)C=C5)=N2)=C1)NC7(CC7)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 549.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Cheng A, Xu Q, Li B, Zhang L, Wang H, Liu C, Han Z, Feng Z. The enhanced energy metabolism in the tumor margin mediated by RRAD promotes the progression of oral squamous cell carcinoma. Cell Death Dis. 2024 May 29;15(5):376. doi: 10.1038/s41419-024-06759-7. PMID: 38811531; PMCID: PMC11137138.