U-50488 Free Base | CAS# 67198-13-4 (free base) | kappa-opioid receptor agonist

MedKoo Cat#: 414392 | Name: U-50488 Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

U-50488 Free Base is a non-peptide, kappa-opioid receptor agonist which has also been found to stimulate the release of adrenocorticotropin (ADRENOCORTICOTROPIC HORMONE) via the release of hypothalamic arginine vasopressin (ARGININE VASOPRESSIN) and CORTICOTROPIN-RELEASING HORMONE.

Chemical Structure

U-50488 Free Base

CAS#67198-13-4 (free base)

Theoretical Analysis

MedKoo Cat#: 414392

Name: U-50488 Free Base

CAS#: 67198-13-4 (free base)

Chemical Formula: C19H26Cl2N2O

Exact Mass: 368.1422

Molecular Weight: 369.33

Elemental Analysis: C, 61.79; H, 7.10; Cl, 19.20; N, 7.59; O, 4.33

Price and Availability

Related CAS #

67197-96-0 (racemic HCl) 114528-79-9 ((-)-U-50488 HCl) 67198-13-4 (free base)

Synonym

U-50488 Free Base; U50488; U 50488; UM1382; UM-1382; UM 1382

IUPAC/Chemical Name

Benzeneacetamide, 3,4-dichloro-N-methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)-, trans-

InChi Key

VQLPLYSROCPWFF-QZTJIDSGSA-N

InChi Code

InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1

SMILES Code

O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 369.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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