MedKoo Cat#: 122175 | Name: (S, R, S)-AHPC-PEG3-amine hydrochloride salt
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S, R, S)-AHPC-PEG3-amine hydrochloride salt is comprised of VHL Ligand coupled to an amine via a PEG3 linker. The 1 VHL Ligand 1 is a synthetic compound used in PROTAC research based on E3 ligase ligand. NH2 group is reactive with carboxylic acids in the presence of coupling reagent such as EDC , or directly with NHS esters, to form a stable amide bond.

Chemical Structure

(S, R, S)-AHPC-PEG3-amine hydrochloride salt
(S, R, S)-AHPC-PEG3-amine hydrochloride salt
CAS#2010159-56-3

Theoretical Analysis

MedKoo Cat#: 122175

Name: (S, R, S)-AHPC-PEG3-amine hydrochloride salt

CAS#: 2010159-56-3

Chemical Formula: C30H45N5O7S

Exact Mass: 619.3040

Molecular Weight: 619.78

Elemental Analysis: C, 58.14; H, 7.32; N, 11.30; O, 18.07; S, 5.17

Price and Availability

Size Price Availability Quantity
100mg USD 800.00 2 Weeks
250mg USD 1,450.00 2 Weeks
500mg USD 2,550.00 2 Weeks
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Related CAS #
No Data
Synonym
(S, R, S)-AHPC-PEG3-amine hydrochloride salt
IUPAC/Chemical Name
(2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChi Key
ZQKKNLXIQLXWLQ-ONBPZOJHSA-N
InChi Code
InChI=1S/C30H45N5O7S/c1-20-26(43-19-33-20)22-7-5-21(6-8-22)16-32-28(38)24-15-23(36)17-35(24)29(39)27(30(2,3)4)34-25(37)18-42-14-13-41-12-11-40-10-9-31/h5-8,19,23-24,27,36H,9-18,31H2,1-4H3,(H,32,38)(H,34,37)/t23-,24+,27-/m1/s1
SMILES Code
CC(N=CS1)=C1C2=CC=C(C=C2)CNC([C@H](C[C@@H](O)C3)N3C([C@H](C(C)(C)C)NC(COCCOCCOCCN)=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 619.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL