MedKoo Cat#: 414371 | Name: Verazide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Verazide is a Tuberculostatic

Chemical Structure

Verazide
Verazide
CAS#93-47-0

Theoretical Analysis

MedKoo Cat#: 414371

Name: Verazide

CAS#: 93-47-0

Chemical Formula: C15H15N3O3

Exact Mass: 285.1113

Molecular Weight: 285.30

Elemental Analysis: C, 63.15; H, 5.30; N, 14.73; O, 16.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Verazide; Nicotazide; NSC180261; NSC-180261; NSC 180261
IUPAC/Chemical Name
(E)-N'-(3,4-dimethoxybenzylidene)isonicotinohydrazide
InChi Key
HPXIKMBHOXLFOR-LICLKQGHSA-N
InChi Code
InChI=1S/C15H15N3O3/c1-20-13-4-3-11(9-14(13)21-2)10-17-18-15(19)12-5-7-16-8-6-12/h3-10H,1-2H3,(H,18,19)/b17-10+
SMILES Code
COc1c(OC)cc(/C=N/NC(c2ccncc2)=O)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 285.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: RUBBO SD, CYMERMAN-CRAIG J. Anti-tuberculous activity of verazide (1-isonicotinoyl-2-veratrylidene hydrazine). Nature. 1955 Nov 5;176(4488):887. doi: 10.1038/176887a0. PMID: 13272716. 2: RUBBO SD, ROUCH LC, EGAN JB, WADDINGTON AL, TELLESSON WG. Chemotherapy of tuberculosis. III. Verazide in the treatment of pulmonary tuberculosis. Am Rev Tuberc. 1958 Aug;78(2):251-8. doi: 10.1164/artpd.1958.78.2.251. PMID: 13559656. 3: RUBBO SD, EDGAR J, VAUGHAN G. Chemotherapy of tuberculosis. I. Antituberculous activity of verazide and related hydrazones. Am Rev Tuberc. 1957 Sep;76(3):331-45. doi: 10.1164/artpd.1957.76.3.331. PMID: 13458717. 4: BARBOLINI G, LOSCHI GC. [Clinico-biological observations on the use of verazide in the therapy of pulmonary tuberculosis]. Clin Ter. 1961 Mar;20:253-73. Italian. PMID: 13686822. 5: RUBBO SD, VAUGHAN G. Chemotherapy of tuberculosis. II. Some observations on the pharmacology of verazide. Am Rev Tuberc. 1957 Sep;76(3):346-59. doi: 10.1164/artpd.1957.76.3.346. PMID: 13458718.