Mefenidil fumarate | CAS# 83153-38-2 | Biochemical

MedKoo Cat#: 576940 | Name: Mefenidil fumarate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mefenidil fumarate is a cerebral vasodilator.

Chemical Structure

Mefenidil fumarate

CAS#83153-38-2 (fumarate)

Theoretical Analysis

MedKoo Cat#: 576940

Name: Mefenidil fumarate

CAS#: 83153-38-2 (fumarate)

Chemical Formula: C16H13N3O42

Exact Mass: 311.0917

Molecular Weight: 311.30

Elemental Analysis: C, 61.73; H, 4.21; N, 13.50; O, 20.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

58261-91-9 (free base) 83153-38-2 (fumarate)

Synonym

McN 2378-46; McN 237846; McN-2378-46; Mefenidil fumarate

IUPAC/Chemical Name

1H-Imidazole-4-acetonitrile, 5-methyl-2-phenyl-, (E)-2-butanedioate (1:1)

InChi Key

BACLFYJGAMBEIX-WLHGVMLRSA-L

InChi Code

InChI=1S/C12H11N3.C4H4O4/c1-9-11(7-8-13)15-12(14-9)10-5-3-2-4-6-10;5-3(6)1-2-4(7)8/h2-6H,7H2,1H3,(H,14,15);1-2H,(H,5,6)(H,7,8)/p-2/b;2-1+

SMILES Code

Cc1[nH]c(nc1CC#N)c2ccccc2.[O-]C(=O)\C=C\C(=O)[O-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 311.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Koehler RC, Wilson DA, Rogers MC, Traystman RJ. Effect of mefenidil on cerebral and peripheral hemodynamics in dogs. J Pharmacol Exp Ther. 1985 May;233(2):327-32. PMID: 3999024. 2. Flaim SF, Stranieri MT, Mathiasen JR, Brannan MD. Effects of mefenidil hydrochloride on cerebral blood flow in conscious and anesthetized rat. Pharmacology. 1986;33(3):167-80. doi: 10.1159/000138214. PMID: 3749246. 3. Hageman WE, Pruss TP. Cardiovascular profile of 5-methyl-2-phenyl-4-imidazole-acetonitrile (MCN-2378), a cerebral vasodilator. Eur J Pharmacol. 1975 Jan;30(1):100-6. doi: 10.1016/0014-2999(75)90209-5. PMID: 1122930.