(S,R,S)-AHPC-Me is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me can be used to synthesize ARV-771, a BET PROTAC degrader.
MedKoo Cat#: 408156
Name: (S,R,S)-AHPC-Me
CAS#: 1948273-02-6
Chemical Formula: C23H32N4O3S
Exact Mass: 444.2195
Molecular Weight: 444.59
Elemental Analysis: C, 62.14; H, 7.26; N, 12.60; O, 10.80; S, 7.21
The following data is based on the product molecular weight 444.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
