MedKoo Cat#: 128880 | Name: 5-iodo A-85380 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

5-iodo A-85380 is an agonist of α4β2 and α6β2 subunit-containing nicotinic acetylcholine receptors (nAChRs).

Chemical Structure

5-iodo A-85380 HCl
5-iodo A-85380 HCl
CAS#1217837-17-6

Theoretical Analysis

MedKoo Cat#: 128880

Name: 5-iodo A-85380 HCl

CAS#: 1217837-17-6

Chemical Formula: C9H13Cl2IN2O

Exact Mass: 0.0000

Molecular Weight: 363.02

Elemental Analysis: C, 29.78; H, 3.61; Cl, 19.53; I, 34.96; N, 7.72; O, 4.41

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
5-iodo A-85380 (hydrochloride); 5-iodo A-85380 HCl; 5-iodo A-85380
IUPAC/Chemical Name
(S)-3-(azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride
InChi Key
ZJVVFYWEBSHGBV-JZGIKJSDSA-N
InChi Code
InChI=1S/C9H11IN2O.2ClH/c10-7-3-9(5-11-4-7)13-6-8-1-2-12-8;;/h3-5,8,12H,1-2,6H2;2*1H/t8-;;/m0../s1
SMILES Code
IC1=CC(OC[C@@H]2CCN2)=CN=C1.Cl.Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 363.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Mogg, A.J., Jones, F.A., Pullar, I.A., et al. Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380. Neuropharmacology 47(6), 848-859 (2004). 2. Huang, L.Z., Campos, C., Ly, J., et al. Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats. Neuropharmacology 60(6), 861-861 (2011).