Maltose monohydrate | CAS# 6363-53-7 | Biochemical

MedKoo Cat#: 576846 | Name: Maltose monohydrate

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Maltose monohydrate is a biochemical sugar.

Chemical Structure

Maltose monohydrate

CAS#6363-53-7

Theoretical Analysis

MedKoo Cat#: 576846

Name: Maltose monohydrate

CAS#: 6363-53-7

Chemical Formula: C12H24O12

Exact Mass: 360.1268

Molecular Weight: 360.31

Elemental Analysis: C, 40.00; H, 6.71; O, 53.28

Price and Availability

Size	Price	Availability	Quantity
25g	USD 250.00	2 Weeks
100g	USD 450.00	2 Weeks

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Synonym

beta-Maltose monohydrate; D-(+)-Maltose monohydrate; Maltose monohydrate

IUPAC/Chemical Name

beta-Maltose monohydrate

InChi Key

HBDJFVFTHLOSDW-DNDLZOGFSA-N

InChi Code

InChI=1S/C12H22O11.H2O/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12;/h1,4-12,14-21H,2-3H2;1H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+;/m0./s1

SMILES Code

O.OC[C@@H](O)[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

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Product Data

Product Data

Instruction

View handling instruction

Biological target:

Maltose monohydrate is a biochemical sugar.

In vitro activity:

Maltose significantly improved the biomass and plantaricin EF production, which increased by 3.35 and 3.99 times comparing to the control without maltose, respectively. The maximum production of plantaricin E and F in fed-batch fermentation were 10.55 mg/L and 22.94 mg/L, respectively. Besides, qPCR results showed that maltose remarkably improved transcription of plnA, plnB, plnD, plnE, plnF, plnG1 and plnH, and heighten transcription of lamR, lamK, hpk6 and rrp6. Reference: Appl Microbiol Biotechnol. 2021 Apr;105(7):2713-2723. https://pubmed.ncbi.nlm.nih.gov/33710357/

In vivo activity:

Lev-resistant (Lev-R) V. alginolyticus exhibits slow growth, reduced pathogenicity and greater resistance to killing by the host, Danio rerio (zebrafish), than Lev-sensitive (Lev-S) V. alginolyticus, suggesting that Lev-R V. alginolyticus triggers a weaker innate immune response in D. rerio than Lev-S V. alginolyticus. Maltose, a crucial metabolite, is significantly downregulated in D. rerio infected with Lev-R V. alginolyticus, and exogenous maltose enhances the immune response of D. rerio to Lev-R V. alginolyticus, leading to better clearance of the infection. Reference: Microb Biotechnol. 2020 Jul;13(4):1213-1227. https://pubmed.ncbi.nlm.nih.gov/32364684/

	Solvent	mg/mL	mM
Solubility
	DMF	15.0	41.63
	DMSO	15.0	41.63
	PBS (pH 7.2)	10.0	27.75
	Water	100.0	277.54

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 360.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

1. Zhao D, Meng F, Zhou L, Lu F, Bie X, Sun J, Lu Z, Lu Y. Maltose effective improving production and regulatory biosynthesis of plantaricin EF in Lactobacillus plantarum 163. Appl Microbiol Biotechnol. 2021 Apr;105(7):2713-2723. doi: 10.1007/s00253-021-11218-w. Epub 2021 Mar 12. PMID: 33710357. 2. Zhang QQ, Liu ZH, Liu LL, Hu G, Lei GL, Wang Y, Cao Y, Wu W, Zhang L, Liao QP. Prebiotic Maltose Gel Can Promote the Vaginal Microbiota From BV-Related Bacteria Dominant to Lactobacillus in Rhesus Macaque. Front Microbiol. 2020 Nov 6;11:594065. doi: 10.3389/fmicb.2020.594065. PMID: 33240248; PMCID: PMC7677408. 3. Jiang M, Yang L, Chen ZG, Lai SS, Zheng J, Peng B. Exogenous maltose enhances Zebrafish immunity to levofloxacin-resistant Vibrio alginolyticus. Microb Biotechnol. 2020 Jul;13(4):1213-1227. doi: 10.1111/1751-7915.13582. Epub 2020 May 4. PMID: 32364684; PMCID: PMC7264874. 4. Ni W, Zhang Q, Liu G, Wang F, Yuan H, Guo Y, Zhang X, Xie F, Li Q, Tai G. Escherichia coli maltose-binding protein activates mouse peritoneal macrophages and induces M1 polarization via TLR2/4 in vivo and in vitro. Int Immunopharmacol. 2014 Jul;21(1):171-80. doi: 10.1016/j.intimp.2014.04.025. Epub 2014 May 10. PMID: 24825603.

In vitro protocol:

In vivo protocol:

1. Jiang M, Yang L, Chen ZG, Lai SS, Zheng J, Peng B. Exogenous maltose enhances Zebrafish immunity to levofloxacin-resistant Vibrio alginolyticus. Microb Biotechnol. 2020 Jul;13(4):1213-1227. doi: 10.1111/1751-7915.13582. Epub 2020 May 4. PMID: 32364684; PMCID: PMC7264874. 2. Ni W, Zhang Q, Liu G, Wang F, Yuan H, Guo Y, Zhang X, Xie F, Li Q, Tai G. Escherichia coli maltose-binding protein activates mouse peritoneal macrophages and induces M1 polarization via TLR2/4 in vivo and in vitro. Int Immunopharmacol. 2014 Jul;21(1):171-80. doi: 10.1016/j.intimp.2014.04.025. Epub 2014 May 10. PMID: 24825603.