Iopamidol monocarboxylic acid | CAS# 87932-11-4 | Biochemical

MedKoo Cat#: 576724 | Name: Iopamidol monocarboxylic acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iopamidol monocarboxylic acid is a non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures.

Chemical Structure

Iopamidol monocarboxylic acid

CAS#87932-11-4

Theoretical Analysis

MedKoo Cat#: 576724

Name: Iopamidol monocarboxylic acid

CAS#: 87932-11-4

Chemical Formula: C14H15I3N2O7

Exact Mass: 703.8013

Molecular Weight: 703.99

Elemental Analysis: C, 23.89; H, 2.15; I, 54.08; N, 3.98; O, 15.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Iopamidol impurity D; Iopamidol monocarboxylic acid

IUPAC/Chemical Name

Benzoic acid, 3-(((2-hydroxy-1-(hydroxymethyl)ethyl)amino)carbonyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-, (S)-

InChi Key

BWAZWHDKQIBKFB-BYPYZUCNSA-N

InChi Code

InChI=1S/C14H15I3N2O7/c1-4(22)12(23)19-11-9(16)6(13(24)18-5(2-20)3-21)8(15)7(10(11)17)14(25)26/h4-5,20-22H,2-3H2,1H3,(H,18,24)(H,19,23)(H,25,26)/t4-/m0/s1

SMILES Code

C[C@H](O)C(=O)Nc1c(I)c(C(=O)O)c(I)c(C(=O)NC(CO)CO)c1I

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 703.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Rodríguez-Romero V, González-Villalva KI, Reyes JL, Franco-Bourland RE, Guízar-Sahagún G, Castañeda-Hernández G, Cruz-Antonio L. A novel, simple and inexpensive procedure for the simultaneous determination of iopamidol and p-aminohippuric acid for renal function assessment from plasma samples in awake rats. J Pharm Biomed Anal. 2015 Mar 25;107:196-203. doi: 10.1016/j.jpba.2014.12.009. Epub 2015 Jan 3. PubMed PMID: 25594899. 2: Müller-Lutz A, Khalil N, Schmitt B, Jellus V, Pentang G, Oeltzschner G, Antoch G, Lanzman RS, Wittsack HJ. Pilot study of Iopamidol-based quantitative pH imaging on a clinical 3T MR scanner. MAGMA. 2014 Dec;27(6):477-85. doi: 10.1007/s10334-014-0433-8. Epub 2014 Feb 26. PubMed PMID: 24570337. 3: Wendel FM, Lütke Eversloh C, Machek EJ, Duirk SE, Plewa MJ, Richardson SD, Ternes TA. Transformation of iopamidol during chlorination. Environ Sci Technol. 2014 Nov 4;48(21):12689-97. doi: 10.1021/es503609s. Epub 2014 Oct 17. PubMed PMID: 25325766. 4: Weiland FL, Marti-Bonmati L, Lim L, Becker HC. Comparison of patient comfort between iodixanol and iopamidol in contrast-enhanced computed tomography of the abdomen and pelvis: a randomized trial. Acta Radiol. 2014 Jul;55(6):715-24. doi: 10.1177/0284185113505277. Epub 2013 Sep 23. PubMed PMID: 24060817. 5: Sun PZ, Longo DL, Hu W, Xiao G, Wu R. Quantification of iopamidol multi-site chemical exchange properties for ratiometric chemical exchange saturation transfer (CEST) imaging of pH. Phys Med Biol. 2014 Aug 21;59(16):4493-504. doi: 10.1088/0031-9155/59/16/4493. Epub 2014 Jul 23. PubMed PMID: 25054859; PubMed Central PMCID: PMC4139413. 6: Tian FX, Xu B, Lin YL, Hu CY, Zhang TY, Gao NY. Photodegradation kinetics of iopamidol by UV irradiation and enhanced formation of iodinated disinfection by-products in sequential oxidation processes. Water Res. 2014 Jul 1;58:198-208. doi: 10.1016/j.watres.2014.03.069. Epub 2014 Apr 5. PubMed PMID: 24762552. 7: Singh RR, Lester Y, Linden KG, Love NG, Atilla-Gokcumen GE, Aga DS. Application of metabolite profiling tools and time-of-flight mass spectrometry in the identification of transformation products of iopromide and iopamidol during advanced oxidation. Environ Sci Technol. 2015 Mar 3;49(5):2983-90. doi: 10.1021/es505469h. Epub 2015 Feb 17. PubMed PMID: 25651339. 8: Akyıldız Akçay F, Bayata S, Semerci T, Yeşil M, Toklu O, Arıkan E, Yakar Tülüce S, Köseoğlu M, Koçağra Yağız I. The effects of iodixanol and iopamidol on adhesion molecule serum levels in patients with angina pectoris undergoing coronary angiography: a randomized study. Anadolu Kardiyol Derg. 2014 Mar;14(2):156-61. doi: 10.5152/akd.2014.4737. Epub 2014 Jan 14. PubMed PMID: 24449631. 9: Borrelli MP, Setacci F, de Donato G, Galzerano G, Benevento D, Mele M, Rosadini D, Messina G, Setacci C. Patient Discomfort during Carotid Artery Stenting: A Comparison Study between Iodixanol versus Iopamidol. Ann Vasc Surg. 2016 Aug 10. pii: S0890-5096(16)30609-4. doi: 10.1016/j.avsg.2016.04.018. [Epub ahead of print] PubMed PMID: 27521830. 10: Zhao C, Arroyo-Mora LE, DeCaprio AP, Sharma VK, Dionysiou DD, O'Shea KE. Reductive and oxidative degradation of iopamidol, iodinated X-ray contrast media, by Fe(III)-oxalate under UV and visible light treatment. Water Res. 2014 Dec 15;67:144-53. doi: 10.1016/j.watres.2014.09.009. Epub 2014 Sep 18. PubMed PMID: 25269106.