MedKoo Cat#: 597799 | Name: Retinyl formyl aspartamate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Retinyl formyl aspartamate is a newly synthesized retinol derivative with higher photostability, and a similar effect on collagenase expression level as retinol.

Chemical Structure

Retinyl formyl aspartamate
Retinyl formyl aspartamate
CAS#442662-22-8

Theoretical Analysis

MedKoo Cat#: 597799

Name: Retinyl formyl aspartamate

CAS#: 442662-22-8

Chemical Formula: C35H46N2O6

Exact Mass: 590.3356

Molecular Weight: 590.76

Elemental Analysis: C, 71.16; H, 7.85; N, 4.74; O, 16.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Retinyl formyl aspartamate; Chebiretipeptide;
IUPAC/Chemical Name
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl (S)-3-formamido-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoate
InChi Key
LSEQFCNTMKUQCA-USEHXCEHSA-N
InChi Code
InChI=1S/C35H46N2O6/c1-25(17-18-29-27(3)14-11-20-35(29,4)5)12-10-13-26(2)19-21-43-32(39)23-30(36-24-38)33(40)37-31(34(41)42-6)22-28-15-8-7-9-16-28/h7-10,12-13,15-19,24,30-31H,11,14,20-23H2,1-6H3,(H,36,38)(H,37,40)/b13-10+,18-17+,25-12+,26-19+/t30-,31-/m0/s1
SMILES Code
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C[C@H](NC=O)C(N[C@H](C(OC)=O)Cc2ccccc2)=O)=O)C(C)(C)CCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 590.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lee MS, Lee KH, Sin HS, Um SJ, Kim JW, Koh BK. A newly synthesized photostable retinol derivative (retinyl N-formyl aspartamate) for photodamaged skin: profilometric evaluation of 24-week study. J Am Acad Dermatol. 2006 Aug;55(2):220-4. Epub 2006 Jun 5. PubMed PMID: 16844502.