MedKoo Cat#: 576466 | Name: Ibuprofen meglumine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ibuprofen meglumine is a nonsteroidal anti-inflammatory drug (NSAID) used for treating pain, fever, and inflammation.

Chemical Structure

Ibuprofen meglumine
Ibuprofen meglumine
CAS#135861-34-6 (meglumine)

Theoretical Analysis

MedKoo Cat#: 576466

Name: Ibuprofen meglumine

CAS#: 135861-34-6 (meglumine)

Chemical Formula: C20H35NO7

Exact Mass: 401.2414

Molecular Weight: 401.50

Elemental Analysis: C, 59.83; H, 8.79; N, 3.49; O, 27.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Artrene; Ibuprofen meglumine; Ibuprofen methylglucamine salt
IUPAC/Chemical Name
D-Glucitol, 1-deoxy-1-(methylamino)-, alpha-methyl-4-(2-methylpropyl)benzeneacetate (salt)
InChi Key
VXVMMZWKWPUJIT-WZTVWXICSA-N
InChi Code
InChI=1S/C13H18O2.C7H17NO5/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;1-8-2-4(10)6(12)7(13)5(11)3-9/h4-7,9-10H,8H2,1-3H3,(H,14,15);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
SMILES Code
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CC(C)Cc1ccc(cc1)C(C)C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 401.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Moore RA, Derry S, Wiffen PJ, Straube S, Aldington DJ. Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions. Eur J Pain. 2015 Oct;19(9):1213-23. doi: 10.1002/ejp.649. Epub 2014 Dec 22. Review. PubMed PMID: 25530283. 2: Derry S, Wiffen PJ, Moore RA. Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults. Cochrane Database Syst Rev. 2015 Jul 14;7:CD011509. doi: 10.1002/14651858.CD011509.pub2. Review. PubMed PMID: 26171993. 3: Ohlsson A, Walia R, Shah SS. Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants. Cochrane Database Syst Rev. 2015 Feb 18;2:CD003481. doi: 10.1002/14651858.CD003481.pub6. Review. PubMed PMID: 25692606. 4: Koh W, Nguyen KP, Jahr JS. Intravenous non-opioid analgesia for peri- and postoperative pain management: a scientific review of intravenous acetaminophen and ibuprofen. Korean J Anesthesiol. 2015 Feb;68(1):3-12. doi: 10.4097/kjae.2015.68.1.3. Epub 2015 Jan 28. Review. PubMed PMID: 25664148; PubMed Central PMCID: PMC4318862.