Z-Ascaridole | CAS# 1354425-86-7 | Biochemical

MedKoo Cat#: 575059 | Name: Z-Ascaridole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Z-Ascaridole is a biochemical.

Chemical Structure

Z-Ascaridole

CAS#1354425-86-7

Theoretical Analysis

MedKoo Cat#: 575059

Name: Z-Ascaridole

CAS#: 1354425-86-7

Chemical Formula: C10H16O2

Exact Mass: 168.1150

Molecular Weight: 168.24

Elemental Analysis: C, 71.39; H, 9.59; O, 19.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

1354425-86-7 512-85-6

Synonym

(+/-)-Ascaridole; (Z)-Ascaridole; Ascarisin; Askaridol; Ascaridole; Ascaridole, (+/-)-; Boldo ascaridole

IUPAC/Chemical Name

(1S,4S)-1-isopropyl-4-methyl-2,3-dioxabicyclo[2.2.2]oct-5-ene

InChi Key

MGYMHQJELJYRQS-ZJUUUORDSA-N

InChi Code

InChI=1S/C10H16O2/c1-8(2)10-6-4-9(3,5-7-10)11-12-10/h4,6,8H,5,7H2,1-3H3/t9-,10+/m1/s1

SMILES Code

CC(C)[C@]12CC[C@@](C)(C=C2)OO1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 168.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Geroldinger G, Tonner M, Hettegger H, Bacher M, Monzote L, Walter M, Staniek K, Rosenau T, Gille L. Mechanism of ascaridole activation in Leishmania. Biochem Pharmacol. 2017 May 15;132:48-62. doi: 10.1016/j.bcp.2017.02.023. Epub 2017 Mar 2. PMID: 28263719. 2. Monzote L, Geroldinger G, Tonner M, Scull R, De Sarkar S, Bergmann S, Bacher M, Staniek K, Chatterjee M, Rosenau T, Gille L. Interaction of ascaridole, carvacrol, and caryophyllene oxide from essential oil of Chenopodium ambrosioides L. with mitochondria in Leishmania and other eukaryotes. Phytother Res. 2018 Sep;32(9):1729-1740. doi: 10.1002/ptr.6097. Epub 2018 Apr 19. PMID: 29672979; PMCID: PMC6208284. 3. Sahli F, Sousa MSE, Vileno B, Lichter J, Lepoittevin JP, Blömeke B, Giménez-Arnau E. Understanding the skin sensitization capacity of ascaridole: a combined study of chemical reactivity and activation of the innate immune system (dendritic cells) in the epidermal environment. Arch Toxicol. 2019 May;93(5):1337-1347. doi: 10.1007/s00204-019-02444-3. Epub 2019 Apr 16. PMID: 30993377.