Iberdomide hydrochloride may be useful in the treatment of systemic lupus erythematosus. Iberdomide significantly reduced Ikaros and Aiolos protein levels in B cells, T cells and monocytes. In SLE PBMC cultures, iberdomide inhibited anti-dsDNA and anti-phospholipid autoantibody production.
MedKoo Cat#: 576457
Name: Iberdomide hydrochloride
CAS#: 1560678-63-8 (HCl)
Chemical Formula: C25H28ClN3O5
Exact Mass: 0.0000
Molecular Weight: 485.96
Elemental Analysis: C, 61.79; H, 5.81; Cl, 7.29; N, 8.65; O, 16.46
The following data is based on the product molecular weight 485.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
