MedKoo Cat#: 413734 | Name: Dihexyverine Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dihexyverine Free Base is an antimuscarinic pharmaceutical drug related to dicycloverine used as a spasmolytic.

Chemical Structure

Dihexyverine Free Base
CAS#561-77-3 (free base)

Theoretical Analysis

MedKoo Cat#: 413734

Name: Dihexyverine Free Base

CAS#: 561-77-3 (free base)

Chemical Formula: C20H35NO2

Exact Mass: 321.2668

Molecular Weight: 321.51

Elemental Analysis: C, 74.72; H, 10.97; N, 4.36; O, 9.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Dihexyverine Free Base; BRN0247822; BRN-0247822; BRN 0247822
IUPAC/Chemical Name
(Bicyclohexyl)-1-carboxylic acid, 2-piperidinoethyl ester
InChi Key
MNSQDVCVWNXBFQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H35NO2/c22-19(23-17-16-21-14-8-3-9-15-21)20(12-6-2-7-13-20)18-10-4-1-5-11-18/h18H,1-17H2
SMILES Code
O=C(C1(C2CCCCC2)CCCCC1)OCCN3CCCCC3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 321.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: FERRON M. [Preliminary clinical study on the use of dihexyverine in obstetrics]. Can Med Assoc J. 1962 Nov 24;87(21):1121-3. PMID: 13944939; PMCID: PMC1849825. 2: MEUNIER H. Sur l'emploi de la dihexyverine en gynécologie [Use of dihexyverine in gynecology]. Gaz Med Fr. 1957 Sep 25;64(18):1533-4. French. PMID: 13480436. 3: ROLLIN G. Essai de traitement des toux spasmodiques par un nouvel antispasmodique de synthèse: la dihexyverine [Trial therapy of spastic cough with a new synthetic antispasmodic: dihexyverine]. Gaz Med Fr. 1955 Dec 25;62(24):1962-3. French. PMID: 13294387. 4: DELECOUR, VITSE, MONNIER. [Clinical experimentation with an antispasmodic, "Dihexyverine", in obstetrical practice]. Lille Med. 1962 Feb;7:143-6. French. PMID: 13885120. 5: FRANCK C, GRANDPIERRE R. Action du dihexyvérine sur le bronchospasme histaminique chez le cobaye [Effect of dihexyverine on histaminic bronchospasm in guinea pigs]. Rev Pathol Gen Physiol Clin. 1955 Mar;55(666):387-9. French. PMID: 14396051. 6: SIMON C, CARRAUD G. Contribution au traitement des entéropathies; a propos des applications digestives d'un nouveau spasmolytique de synthèse: dihexyvérine [Contribution to the treatment of enteropathies; digestive application of a new synthetic spasmolytic--dihexyverine]. Sem Hop. 1955 Mar 20;31(18/2):91-3. French. PMID: 14373023. 7: FRANCOIS A. Des indications obstétricales prénatales de la dihexyvérine [Prenatal obstetric indications for dihexyverine]. Sem Hop. 1955 Sep 30;31(57):2980-3. French. PMID: 13267510. 8: FERRON M. [Preliminary clinical study on the use of dihexyverine in obstetrics]. Union Med Can. 1962 Aug;91:832-6. French. PMID: 13892604. 9: BILWEIS J. Etude expérimentale sur l'utilisation de la dihexyverine au cours du travail obstétrical dirigé selon la méthode d'accouchement physiologiquement accéléré [Experimental study on the use of dihexyverine in obstetrical labor by the physiological accelerated labor method]. Concours Med. 1958 Mar 8;80(10):1193-5. French. PMID: 13511938. 10: FRANCK C, LAMARCHE M, ROZE P. Modifications de la résistance au déficit en oxygène chez le cobaye après administration de dihexyvérine [Modifications in the resistance to oxygen deficiency in the guinea pig after administration of dihexyverine]. C R Seances Soc Biol Fil. 1955 Dec;149(23-24):2201-2. French. PMID: 13317334.