MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 413516 | Name: Dembrexine Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dembrexine Free Base is a mucolytic agent which reduces the viscosity of respiratory mucus. It improves movement of mucus in small airways.

Chemical Structure

Dembrexine Free Base
Dembrexine Free Base
CAS#83200-09-3 (free base)

Theoretical Analysis

MedKoo Cat#: 413516

Name: Dembrexine Free Base

CAS#: 83200-09-3 (free base)

Chemical Formula: C13H17Br2NO2

Exact Mass: 376.9626

Molecular Weight: 379.09

Elemental Analysis: C, 41.19; H, 4.52; Br, 42.16; N, 3.69; O, 8.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
83200-09-3 (free base) 52702-51-9 (HCl)
Synonym
Dembrexine Free Base; Dembroxol; Dembroxolum
IUPAC/Chemical Name
trans-4-((3,5-Dibromosalicyl)amino)cyclohexanol
InChi Key
GEDPQKGMHLHFOZ-XYPYZODXSA-N
InChi Code
InChI=1S/C13H17Br2NO2/c14-9-5-8(13(18)12(15)6-9)7-16-10-1-3-11(17)4-2-10/h5-6,10-11,16-18H,1-4,7H2/t10-,11-
SMILES Code
O[C@H]1CC[C@H](NCC2=CC(Br)=CC(Br)=C2O)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
To be determined 0.0 0.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 379.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Paterson S. Otitis media with effusion in the boxer: a report of seven cases. J Small Anim Pract. 2017 Dec 12. doi: 10.1111/jsap.12801. Epub ahead of print. PMID: 29231979. 2: Matthews AG, Hackett IJ, Lawton WA. The mucolytic effect of Sputolosin in horses with respiratory disease. Vet Rec. 1988 Jan 30;122(5):106-8. doi: 10.1136/vr.122.5.106. PMID: 3363832. 3: Bauer E, McDougall J, Cameron BD. The trans-cis isomerization of trans-4'-(2-hydroxy-3,5-dibromo-benzylamino)cyclohexanol in vivo and in vitro in different species. Xenobiotica. 1986 Jul;16(7):625-33. doi: 10.3109/00498258609043552. PMID: 3751117.