MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 413234 | Name: Colistin nonapeptide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Colistin nonapeptide binds to LPS and possesses antiendotoxin activity

Chemical Structure

Colistin nonapeptide
Colistin nonapeptide
CAS#32530-94-2 (free base)

Theoretical Analysis

MedKoo Cat#: 413234

Name: Colistin nonapeptide

CAS#: 32530-94-2 (free base)

Chemical Formula: C40H76N14O11

Exact Mass: 928.5818

Molecular Weight: 929.14

Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 51.71; H, 8.25; N, 21.11; O, 18.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
32530-94-2 (free base) 52396-32-4 (HCl)
Synonym
Colistin nonapeptide
IUPAC/Chemical Name
2-amino-N-(4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)-3-hydroxybutanamide
InChi Key
WNPBEUWOUYCJJR-UHFFFAOYSA-N
InChi Code
InChI=1S/C40H76N14O11/c1-19(2)17-28-37(62)49-23(7-12-41)32(57)48-26(10-15-44)36(61)54-31(22(6)56)40(65)46-16-11-27(50-33(58)25(9-14-43)51-39(64)30(45)21(5)55)35(60)47-24(8-13-42)34(59)52-29(18-20(3)4)38(63)53-28/h19-31,55-56H,7-18,41-45H2,1-6H3,(H,46,65)(H,47,60)(H,48,57)(H,49,62)(H,50,58)(H,51,64)(H,52,59)(H,53,63)(H,54,61)
SMILES Code
CC(CC1NC(C(NC(C(NC(C(NC(C(NC(C(C(O)C)N)=O)CCN)=O)CCNC(C(C(O)C)NC(C(NC(C(NC1=O)CCN)=O)CCN)=O)=O)=O)CCN)=O)CC(C)C)=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 929.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Warren HS, Kania SA, Siber GR. Binding and neutralization of bacterial lipopolysaccharide by colistin nonapeptide. Antimicrob Agents Chemother. 1985 Jul;28(1):107-12. doi: 10.1128/aac.28.1.107. PMID: 2412488; PMCID: PMC176319. 2: Ito-Kagawa M, Koyama Y. Studies on the selectivity of action of colistin, colistin nonapeptide and colistin heptapeptide on the cell envelope of Escherichia coli. J Antibiot (Tokyo). 1984 Aug;37(8):926-8. doi: 10.7164/antibiotics.37.926. PMID: 6384168.

View History

BP Lipid 101

BP Lipid 101

Featured