MedKoo Cat#: 524565 | Name: CB-13
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CB-13, also known as SAB-378, CRB-13, is a potent, orally active CB1/CB2 receptor agonist with limited brain penetration (EC50 values are 6.1 and 27.9 nM for CB1 and CB2 receptors respectively). It displays antihyperalgesic activity in a rat model of neuropathic pain with no CNS side effects.

Chemical Structure

CB-13
CB-13
CAS#432047-72-8

Theoretical Analysis

MedKoo Cat#: 524565

Name: CB-13

CAS#: 432047-72-8

Chemical Formula: C26H24O2

Exact Mass: 368.1776

Molecular Weight: 386.47

Elemental Analysis: C, 84.75; H, 6.57; O, 8.68

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
50mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
CB-13; CB 13; CB13; CRA-13; CRA 13; CRA13; USAB-378; SAB 378; SAB378.
IUPAC/Chemical Name
1-Naphthalenyl(4-(pentyloxy)-1-naphthalenyl)methanone
InChi Key
RSUMDJRTAFBISX-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H24O2/c1-2-3-8-18-28-25-17-16-24(21-13-6-7-14-22(21)25)26(27)23-15-9-11-19-10-4-5-12-20(19)23/h4-7,9-17H,2-3,8,18H2,1H3
SMILES Code
CCCCCOc1ccc(C(=O)c2cccc3ccccc23)c4ccccc14
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 386.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Dziadulewicz, E.K., Bevan, S.J., Brain, C.T., et al. Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: A potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration. Journal of Medicinal Chemistry 50, 3851-3856 (2007).