MedKoo Cat#: 575187 | Name: Azatadine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azatadine is a first-generation antihistamine and anticholinergic. It has been succeeded by both loratadine and desloratadine.

Chemical Structure

Azatadine
Azatadine
CAS#3964-81-6 (free base)

Theoretical Analysis

MedKoo Cat#: 575187

Name: Azatadine

CAS#: 3964-81-6 (free base)

Chemical Formula: C20H22N2

Exact Mass: 290.1783

Molecular Weight: 290.41

Elemental Analysis: C, 82.72; H, 7.64; N, 9.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Azatadine
IUPAC/Chemical Name
6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
InChi Key
SEBMTIQKRHYNIT-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3
SMILES Code
CN1CCC(=C2c3ccccc3CCc4cccnc24)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 290.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Baroody FM, Naclerio RM. Antiallergic effects of H1-receptor antagonists. Allergy. 2000;55 Suppl 64:17-27. doi: 10.1034/j.1398-9995.2000.00803.x. PMID: 11291777. 2. Azatadine (optimine)--a new antihistamine. Med Lett Drugs Ther. 1977 Sep 23;19(19):77-9. PMID: 19692. 3. Zhu YR, Jia YY, Jiang L, Wang C, Ding LK, Yang J, Li L, Zhao PX, Liu WX, Yi-Ding, Wang L, Wen AD. Determination of azatadine in human plasma by liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Aug 1;879(23):2189-93. doi: 10.1016/j.jchromb.2011.05.050. Epub 2011 Jun 12. PMID: 21737359.