BU-224 HCl | CAS#205437-64-5 | Putative I2 antagonist

MedKoo Cat#: 556105 | Name: BU-224 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BU-224 is a Putative I2 antagonist; and a high affinity ligand for the imidazoline I2 binding site (Ki = 2.1 nM). BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease.

Chemical Structure

BU-224 HCl

CAS#205437-64-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 556105

Name: BU-224 HCl

CAS#: 205437-64-5 (HCl)

Chemical Formula: C12H12ClN3

Exact Mass: 0.0000

Molecular Weight: 233.70

Elemental Analysis: C, 61.67; H, 5.18; Cl, 15.17; N, 17.98

Price and Availability

Size	Price	Availability
50mg	USD 550.00	2 Weeks
100mg	USD 950.00	2 Weeks
200mg	USD 1,650.00	2 Weeks
500mg	USD 2,650.00	2 Weeks
1g	USD 3,650.00	2 Weeks
2g	USD 6,250.00	2 Weeks

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Related CAS #

205437-64-5 (HCl) 187173-05-3 (free base)

Synonym

BU-224 HCl; BU-224; BU 224; BU224;

IUPAC/Chemical Name

2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride

InChi Key

DDFHQXAQWZWRSQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H11N3.ClH/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12;/h1-6H,7-8H2,(H,13,14);1H

SMILES Code

[H]Cl.C1(C2=NCCN2)=NC3=CC=CC=C3C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 233.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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