QD232 | CAS#1527467-32-8 | Quinazolinedione-based redox modulator

MedKoo Cat#: 463309 | Name: QD232

Description:

WARNING: This product is for research use only, not for human or veterinary use.

QD232 is a novel inhibitor of cell proliferation, adhesion, and migration, leading to pancreatic cancer cell death by apoptosis and exerting ROS-mediated decrease in Src/FAK and STAT3 phosphorylation.

Chemical Structure

QD232

CAS#1527467-32-8

Theoretical Analysis

MedKoo Cat#: 463309

Name: QD232

CAS#: 1527467-32-8

Chemical Formula: C16H11N3O3

Exact Mass: 293.0800

Molecular Weight: 293.28

Elemental Analysis: C, 65.53; H, 3.78; N, 14.33; O, 16.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

QD232; QD 232; QD-232;

IUPAC/Chemical Name

6-((3-acetylphenyl)amino)quinazoline-5,8-dione

InChi Key

ISLYLVODAYGJNW-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H11N3O3/c1-9(20)10-3-2-4-11(5-10)19-13-6-14(21)15-12(16(13)22)7-17-8-18-15/h2-8,19H,1H3

SMILES Code

O=C(C(NC1=CC=CC(C(C)=O)=C1)=C2)C3=CN=CN=C3C2=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 293.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Pathania D, Kuang Y, Sechi M, Neamati N. Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells. Br J Pharmacol. 2015 Jan;172(1):50-63. doi: 10.1111/bph.12855. PMID: 25047070; PMCID: PMC4280967.