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MedKoo Cat#: 463308 | Name: LDDN-0003499

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LDDN-0003499 is a novel Src family tyrosine kinase inhibitor with anti-inflammatory effects in response to Aß stimulation of microglia.

Chemical Structure

LDDN-0003499
LDDN-0003499
CAS#331662-51-2

Theoretical Analysis

MedKoo Cat#: 463308

Name: LDDN-0003499

CAS#: 331662-51-2

Chemical Formula: C16H13Cl2N3O2

Exact Mass: 349.0385

Molecular Weight: 350.20

Elemental Analysis: C, 54.88; H, 3.74; Cl, 20.25; N, 12.00; O, 9.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LDDN-0003499; LDDN0003499; LDDN 0003499;
IUPAC/Chemical Name
N-(2,4-dichlorophenyl)-6,7-dimethoxyquinazolin-4-amine
InChi Key
PKEYRKYHSXFGBA-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H13Cl2N3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21)
SMILES Code
COC1=CC2=NC=NC(NC3=CC=C(Cl)C=C3Cl)=C2C=C1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 350.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Manocha GD, Puig KL, Austin SA, Seyb K, Glicksman MA, Combs CK. Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis. PLoS One. 2015 Jul 10;10(7):e0132604. doi: 10.1371/journal.pone.0132604. PMID: 26161952; PMCID: PMC4498792.