MedKoo Cat#: 462760 | Name: Vasoactive intestinal peptide (22-28)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Vasoactive intestinal peptide (22-28) is a biochemical that has shown to stimulate tumor cell growth.

Chemical Structure

Vasoactive intestinal peptide (22-28)
Vasoactive intestinal peptide (22-28)
CAS#47900-24-3

Theoretical Analysis

MedKoo Cat#: 462760

Name: Vasoactive intestinal peptide (22-28)

CAS#: 47900-24-3

Chemical Formula: C53H85N15O14

Exact Mass: 1155.6400

Molecular Weight: 1156.35

Elemental Analysis: C, 55.05; H, 7.41; N, 18.17; O, 19.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Vip (22-28);
IUPAC/Chemical Name
L-Aspartamide, L-tyrosyl-L-leucyl-L-asparaginyl-L-seryl-L-isoleucyl-L-leucyl-
InChi Key
QMLXCJQZMNVNMU-ABCDUJAMSA-N
InChi Code
InChI=1S/C53H85N15O14/c1-27(2)24-36(45(74)60-26-41(72)67-22-8-11-37(67)47(76)65-42(28(3)4)49(78)63-35(52(81)82)10-7-21-59-53(57)58)64-50(79)43(29(5)6)66-48(77)38-12-9-23-68(38)51(80)34(18-20-40(56)71)62-46(75)33(17-19-39(55)70)61-44(73)32(54)25-30-13-15-31(69)16-14-30/h13-16,27-29,32-38,42-43,69H,7-12,17-26,54H2,1-6H3,(H2,55,70)(H2,56,71)(H,60,74)(H,61,73)(H,62,75)(H,63,78)(H,64,79)(H,65,76)(H,66,77)(H,81,82)(H4,57,58,59)/t32-,33-,34-,35-,36-,37-,38-,42-,43-/m0/s1
SMILES Code
CC(C[C@@H](C(NCC(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)C(C)C)=O)=O)=O)NC([C@H](C(C)C)NC([C@@H]2CCCN2C([C@@H](NC([C@@H](NC([C@H](Cc3ccc(O)cc3)N)=O)CCC(N)=O)=O)CCC(N)=O)=O)=O)=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,156.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Romualdi P, Rosenberger JG, Gozzini L, Cox BM. Vasoactive intestinal polypeptide carboxy-terminal fragment, VIP(22-28), and other fragments of VIP, in the central nervous system of the rat. Peptides. 1989 May-Jun;10(3):621-6. doi: 10.1016/0196-9781(89)90153-8. PMID: 2780421. 2: Romualdi P, Lesa G, Donatini A, Balboni G, Tomatis R, Ferri S. Alterations in vasoactive intestinal polypeptide-related peptides after pentylenetetrazole- induced seizures in rat brain. Eur J Pharmacol. 1992 Dec 15;229(2-3):149-53. doi: 10.1016/0014-2999(92)90549-j. PMID: 1490518. 3: Scholar EM, Paul S. Stimulation of tumor cell growth by vasoactive intestinal peptide. Cancer. 1991 Mar 15;67(6):1561-4. doi: 10.1002/1097-0142(19910315)67:6<1561::aid-cncr2820670617>3.0.co;2-z. PMID: 2001545. 4: Giannetti A, Fantini F, Cimitan A, Pincelli C. Vasoactive intestinal polypeptide and substance P in the pathogenesis of atopic dermatitis. Acta Derm Venereol Suppl (Stockh). 1992;176:90-2. PMID: 1282289.