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MedKoo Cat#: 564379 | Name: VU6007705

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VU6007705 is a muscarinic acetylcholine receptor positive allosteric modulator (PAM).

Chemical Structure

VU6007705
VU6007705
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564379

Name: VU6007705

CAS#: NONE

Chemical Formula: C26H32N4O3S

Exact Mass: 480.2195

Molecular Weight: 480.63

Elemental Analysis: C, 64.97; H, 6.71; N, 11.66; O, 9.99; S, 6.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
VU-6007705; VU 6007705; VU6007705
IUPAC/Chemical Name
(R)-1-((1H-Indazol-5-yl)sulfonyl)-N-propyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)piperidine-4-carboxamide
InChi Key
YUMBEWHZSRMENI-RUZDIDTESA-N
InChi Code
InChI=1S/C26H32N4O3S/c1-2-14-30(25-9-5-7-19-6-3-4-8-23(19)25)26(31)20-12-15-29(16-13-20)34(32,33)22-10-11-24-21(17-22)18-27-28-24/h3-4,6,8,10-11,17-18,20,25H,2,5,7,9,12-16H2,1H3,(H,27,28)/t25-/m1/s1
SMILES Code
O=C(C1CCN(S(=O)(C2=CC3=C(NN=C3)C=C2)=O)CC1)N(CCC)[C@@H]4CCCC5=C4C=CC=C5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 480.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Berizzi AE, Bender AM, Lindsley CW, Conn PJ, Sexton PM, Langmead CJ, Christopoulos A. Structure-Activity Relationships of Pan-Gα(q/11) Coupled Muscarinic Acetylcholine Receptor Positive Allosteric Modulators. ACS Chem Neurosci. 2018 Jul 18;9(7):1818-1828. doi: 10.1021/acschemneuro.8b00136. Epub 2018 Apr 30. PubMed PMID: 29683647; PubMed Central PMCID: PMC6106869.