(S,R,S)-AHPC-C3-NH2 hydrochloride is a ProTAC building block. (S,R,S)-AHPC-C3-NH2 hydrochloride enables the synthesis of molecules for targeted protein degradation. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand and an alkyl-chain crosslinker with pendant amine for reactivity with an acid on the target warhead. This product has no formal name at the moment. For the convenience of communication, a temporal code was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
-AHPC-C3-NH2 hydrochloride3832.jpg "(S,R,S)-AHPC-C3-NH2 hydrochloride")
MedKoo Cat#: 121175
Name: (S,R,S)-AHPC-C3-NH2 hydrochloride
CAS#: 2940858-65-9
Chemical Formula: C26H38ClN5O4S
Exact Mass: 551.2333
Molecular Weight: 552.13
Elemental Analysis: C, 56.56; H, 6.94; Cl, 6.42; N, 12.68; O, 11.59; S, 5.81
The following data is based on the product molecular weight 552.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
