PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor. It has antidiabetic, anticancer and anti-allergic activity. Inactivation of PDKs using inhibitors such as PDK4-IN-1 hydrochloride displays a higher degree of efficacy in tozasertib-resistant cells.
MedKoo Cat#: 462458
Name: PDK4-IN-1 hydrochloride
CAS#: 2310262-11-2 (HCl)
Chemical Formula: 22H20ClN3O2
Exact Mass: 393.1244
Molecular Weight: 393.87
Elemental Analysis: C, 67.09; H, 5.12; Cl, 9.00; N, 10.67; O, 8.12
The following data is based on the product molecular weight 393.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
