MedKoo Cat#: 462290 | Name: FPA 124
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FPA 124 is a cell-permeable copper complex and a selective Akt inhibitor.

Chemical Structure

FPA 124
FPA 124
CAS#902779-59-3

Theoretical Analysis

MedKoo Cat#: 462290

Name: FPA 124

CAS#: 902779-59-3

Chemical Formula: C11H9Cl2CuN3O2S

Exact Mass: 379.9089

Molecular Weight: 381.72

Elemental Analysis: C, 34.61; H, 2.38; Cl, 18.57; Cu, 16.65; N, 11.01; O, 8.38; S, 8.40

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
FPA 124; FPA124; FPA-124; Akt Inhibitor XI
IUPAC/Chemical Name
Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex
InChi Key
HZRXQEVFXXQYFS-VBPDOGLUSA-L
InChi Code
InChI=1S/C11H9N3O2S.2ClH.Cu/c12-11(17)14-13-5-7-6-16-9-4-2-1-3-8(9)10(7)15;;;/h1-6H,(H3,12,14,17);2*1H;/q;;;+2/p-2/b13-5+;;;
SMILES Code
O=C1C2=CC=CC=C2OC=C1/C=[N]3[Cu]([Cl-])([S]=C(N)N\3)[Cl-].[2+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 381.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Barve V, Ahmed F, Adsule S, et al. Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells. J Med Chem. 2006;49(13):3800-3808. doi:10.1021/jm051068y 2: Biscetti F, Straface G, Arena V, et al. Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation. Cardiovasc Diabetol. 2009;8:49. Published 2009 Sep 8. doi:10.1186/1475-2840-8-49.