Synonym
HM03; HM 03; HM-03; NSC130813; NSC 130813; NSC-130813; F06;
IUPAC/Chemical Name
4-((6-chloro-2-methoxyacridin-9-yl)amino)-2-((4-methylpiperazin-1-yl)methyl)phenol
InChi Key
SUSDGTMJKOGWSZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H27ClN4O2/c1-30-9-11-31(12-10-30)16-17-13-19(4-8-25(17)32)28-26-21-6-3-18(27)14-24(21)29-23-7-5-20(33-2)15-22(23)26/h3-8,13-15,32H,9-12,16H2,1-2H3,(H,28,29)
SMILES Code
ClC1=CC=C2C(N=C(C=CC(OC)=C3)C3=C2NC4=CC(CN5CCN(C)CC5)=C(O)C=C4)=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
462.98
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Sturaro C, Ruzza C, Ferrari F, Pola P, Argentieri M, Frezza A, Marzola E,
Bettegazzi B, Cattaneo S, Pietra C, Malfacini D, Calò G. In vitro
pharmacological characterization of growth hormone secretagogue receptor ligands
using the dynamic mass redistribution and calcium mobilization assays. Eur J
Pharmacol. 2024 Oct 15;981:176880. doi: 10.1016/j.ejphar.2024.176880. Epub 2024
Aug 10. PMID: 39128804.
2: Han JH, Shim H, Shin JH, Kim KS. Antagonistic Activities of Bacillus spp.
Strains Isolated from Tidal Flat Sediment Towards Anthracnose Pathogens
Colletotrichum acutatum and C. gloeosporioides in South Korea. Plant Pathol J.
2015 Jun;31(2):165-75. doi: 10.5423/PPJ.OA.03.2015.0036. Epub 2015 Jun 30. PMID:
26060435; PMCID: PMC4453997.
3: Anti-mucin: MAbs RT03, HTA, HM02, HM03. Hybridoma. 2000 Dec;19(6):509. doi:
10.1089/027245700750054075. PMID: 11153074.
4: Shin CY, Lee WJ, Kim DJ, Park CS, Park SH, Ko KH. Production and
characterization of monoclonal antibodies against human airway mucins.
Hybridoma. 1999 Oct;18(5):457-63. doi: 10.1089/hyb.1999.18.457. PMID: 10600033.
