MedKoo Cat#: 584468 | Name: TC KHNS 11
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TC KHNS 11 is a potent and selective PI 3-kinase δ inhibitor that is orally bioavailable.

Chemical Structure

TC KHNS 11
TC KHNS 11
CAS#1431540-99-6

Theoretical Analysis

MedKoo Cat#: 584468

Name: TC KHNS 11

CAS#: 1431540-99-6

Chemical Formula: C28H24N6O3

Exact Mass: 492.1910

Molecular Weight: 492.54

Elemental Analysis: C, 68.28; H, 4.91; N, 17.06; O, 9.74

Price and Availability

Size Price Availability Quantity
50mg USD 750.00 2-3 weeks
100mg USD 1,250.00 2-3 weeks
200mg USD 1,950.00 2-3 weeks
1g USD 4,650.00 2-3 weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
TC KHNS 11
IUPAC/Chemical Name
5-[4-[3-[(4-Acetyl-1-piperazinyl)carbonyl]phenyl]-6-quinazolinyl]-2-methoxy-3-pyridinecarbonitrile
InChi Key
QYTXJLQBSYAMGR-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H24N6O3/c1-18(35)33-8-10-34(11-9-33)28(36)21-5-3-4-20(12-21)26-24-14-19(6-7-25(24)31-17-32-26)23-13-22(15-29)27(37-2)30-16-23/h3-7,12-14,16-17H,8-11H2,1-2H3
SMILES Code
N#CC1=CC(C2=CC3=C(C4=CC=CC(C(N5CCN(C(C)=O)CC5)=O)=C4)N=CN=C3C=C2)=CN=C1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 492.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Hoegenauer et al (2016) Discovery and pharmacological characterization of novel quinazoline-based PI3K delta-selective inhibitors. ACS Med.Chem.Lett. 7 762 PMID: 27563400