Synonym
Fosfonet sodium, Disodium phosphonoacetate, Disodium carboxymethylphosphonate Disodium phosphonoacetate monohydrate
IUPAC/Chemical Name
sodium;2-phosphonoacetic acid
InChi Key
KNBQMQYQYHZXSX-UHFFFAOYSA-N
InChi Code
InChI=1S/C2H5O5P.Na/c3-2(4)1-8(5,6)7;/h1H2,(H,3,4)(H2,5,6,7);/q;+1
SMILES Code
C(C(=O)O)P(=O)(O)O.[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
162.01
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Verrier ER, Weiss A, Bach C, Heydmann L, Turon-Lagot V, Kopp A, El Saghire H, Crouchet E, Pessaux P, Garcia T, Pale P, Zeisel MB, Sureau C, Schuster C, Brino L, Baumert TF. Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets. Gut. 2020 Jan;69(1):158-167. doi: 10.1136/gutjnl-2018-317065. Epub 2019 Mar 4. PubMed PMID: 30833451; PubMed Central PMCID: PMC6943243.
2: Lacerda-Abreu MA, Russo-Abrahão T, Cosentino-Gomes D, Nascimento MTC, Carvalho-Kelly LF, Gomes T, Rodrigues MF, König S, Rumjanek FD, Monteiro RQ, Meyer-Fernandes JR. H(+)-dependent inorganic phosphate transporter in breast cancer cells: Possible functions in the tumor microenvironment. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2180-2188. doi: 10.1016/j.bbadis.2019.04.015. Epub 2019 Apr 26. PubMed PMID: 31034992.
3: Manning LR, Manning JM. Phosphorylation of Serine Induces Lysine p K(a) Increases in Histone N-Termini and Signaling for Acetylation. Transcription Implications. Biochemistry. 2018 Dec 18;57(50):6816-6821. doi: 10.1021/acs.biochem.8b01040. Epub 2018 Dec 5. PubMed PMID: 30431267.
