MedKoo Cat#: 563082 | Name: EMD57439

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EMD57439 is a PDE 3 inhibitor.

Chemical Structure

EMD57439
EMD57439
CAS#148714-88-9

Theoretical Analysis

MedKoo Cat#: 563082

Name: EMD57439

CAS#: 148714-88-9

Chemical Formula: C22H23N3O4S

Exact Mass: 425.1409

Molecular Weight: 425.50

Elemental Analysis: C, 62.10; H, 5.45; N, 9.88; O, 15.04; S, 7.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
EMD57439; EMD-57439; EMD 57439;
IUPAC/Chemical Name
(S)-5-(1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-6-methyl-3,6-dihydro-2H-1,3,4-thiadiazin-2-one
InChi Key
IZLRMTJLQCLMKF-ZDUSSCGKSA-N
InChi Code
InChI=1S/C22H23N3O4S/c1-13-20(23-24-22(27)30-13)15-6-8-17-14(11-15)5-4-10-25(17)21(26)16-7-9-18(28-2)19(12-16)29-3/h6-9,11-13H,4-5,10H2,1-3H3,(H,24,27)/t13-/m0/s1
SMILES Code
O=C1S[C@@H](C)C(C2=CC3=C(N(C(C4=CC=C(OC)C(OC)=C4)=O)CCC3)C=C2)=NN1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 425.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kusakari Y, Hongo K, Kawai M, Konishi M, Kurihara S. Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca2+ in tetanized rat ventricular myocytes. J Physiol Sci. 2006 Jun;56(3):219-26. Epub 2006 Jun 3. PubMed PMID: 16839456. 2: Lipscomb-Allhouse S, Mulligan IP, Ashley CC. The effects of the inotropic agent EMD 57033 on activation and relaxation kinetics in frog skinned skeletal muscle. Pflugers Arch. 2001 May;442(2):171-7. PubMed PMID: 11417210.