MedKoo Cat#: 533795 | Name: MCU-i11
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.

Chemical Structure

MCU-i11
MCU-i11
CAS#902903-59-7

Theoretical Analysis

MedKoo Cat#: 533795

Name: MCU-i11

CAS#: 902903-59-7

Chemical Formula: C28H28N4O5S

Exact Mass: 532.1780

Molecular Weight: 532.62

Elemental Analysis: C, 63.14; H, 5.30; N, 10.52; O, 15.02; S, 6.02

Price and Availability

Size Price Availability Quantity
10mg USD 650.00 2 Weeks
25mg USD 1,050.00 2 Weeks
50mg USD 1,650.00 2 Weeks
1g USD 6,450.00 2 Weeks
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Related CAS #
No Data
Synonym
MCU-i11; MCU i11; MCUi11;
IUPAC/Chemical Name
2-(7-Acetyl-3-benzyl-2,4-dioxo-3,4,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-1(2H)-yl)-N-(4-ethoxyphenyl)acetamide
InChi Key
YKJDMJLUMXISKF-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H28N4O5S/c1-3-37-21-11-9-20(10-12-21)29-24(34)17-32-27-25(22-13-14-30(18(2)33)16-23(22)38-27)26(35)31(28(32)36)15-19-7-5-4-6-8-19/h4-12H,3,13-17H2,1-2H3,(H,29,34)
SMILES Code
O=C(NC1=CC=C(OCC)C=C1)CN(C2=C(C3=C(CN(C(C)=O)CC3)S2)C(N4CC5=CC=CC=C5)=O)C4=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 532.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Di Marco G, Vallese F, Jourde B, et al. A High-Throughput Screening Identifies MICU1 Targeting Compounds. Cell Rep. 2020;30(7):2321-2331.e6. doi:10.1016/j.celrep.2020.01.081