BNC210, also known as IW-2143, is an anxiolytic drug that acts via negative allosteric modulation of the α7-nicotinic acetylcholine receptor. It is currently being investigated for the treatment of post traumatic stress disorder. The drug has demonstrated clinically significant anxiety reduction in both animal models and in Phase I trials.
MedKoo Cat#: 555721
Name: BNC-210
CAS#: 13589-06-5 (free base)
Chemical Formula: C17H23N3O3
Exact Mass: 317.1739
Molecular Weight: 317.39
Elemental Analysis: C, 64.33; H, 7.30; N, 13.24; O, 15.12
The following data is based on the product molecular weight 317.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
